ReviewJournal of functional biomaterials2024
Molar Distalization by Clear Aligners with Sequential Distalization Protocol: A Systematic Review and Meta-Analysis.
Review in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness and accuracy of clear aligners in non-extraction Class II correction: a systematic review of maxillary molar distalization and rotation in the permanent dentition.The Angle orthodontist · 2025Pooled it
- Clinical Outcomes of Sequential Distalization with Clear Aligners: A Systematic Review and Meta-Analysis.Dentistry journal · 2026Review
- Clear aligners for Class II correction in growing patients: elastics vs mandibular advancement.The Angle orthodontist · 2026Article
- Potential for vertical control using direct 3D‑printed mandibular advancement clear aligners.Clinical oral investigations · 2026Article
- Clear Aligner Therapy Assisted by Implant Anchorage and S-Shaped Root Control Attachments for Anterior Open Bite Correction: A 30-Month Treatment Case Report.Case reports in dentistry · 2026Article
- Effects of Bonded Rapid Palatal Expander on Vertical Dimension: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Clinical Efficacy of Clear Aligners in Class II Malocclusion: From Pediatric to Adult Cases-A Narrative Review.Journal of functional biomaterials · 2025Review
- Maxillary molar distalization with invisalign in adult patients: a preliminary study using iTero-created digital models.BMC oral health · 2025Article
- Effects of maxillary molar distalization using clear aligners during the mixed dentition and early permanent dentition with 3 types of Class II traction: a three-dimensional finite element analysis.BMC oral health · 2025Article
- Force distributions associated with different elastic traction methods for maxillary dentition distalization by clear aligners: an in-vitro study.BMC oral health · 2025Article
- The effect of maxillary premolar distalization with different designed clear aligners: a 4D finite element study with staging simulation.Progress in orthodontics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
introductionWith the popularity of clear aligners, the sequential distalization protocol has been more commonly used for molar distalization. However, the amount of molar distalization that can be achieved, as well as the accompanying side effects on the sagittal dimension, are unclear.
methodsRegistered with PROSPERO (CRD42023447211), relevant original studies were screened from seven databases (MEDLINE [PubMed], EBSCOhost, Web of Science, Elsevier [SCOPUS], Cochrane, LILACS [Latin American and Caribbean Health Sciences Literature], and Google Scholar) supplemented by a manual search of the references of the full-reading manuscripts by two investigators independently. A risk of bias assessment was conducted, relevant data were extracted, and meta-analysis was performed using RStudio.
resultsAfter the screening, 13 articles (11 involving maxillary distalization, two involving mandibular distalization) met the inclusion criteria. All studies had a high or medium risk of bias. The meta-analysis revealed that the maxillary first molar (U6) mesiobuccal cusp was distalized 2.07 mm [1.38 mm, 2.77 mm] based on the post-distalization dental model superimposition, and the U6 crown was distalized 2.00 mm [0.77 mm, 3.24 mm] based on the post-treatment lateral cephalometric evaluation. However, the U6 mesiobuccal root showed less distalization of 1.13 mm [-1.34 mm, 3.60 mm], indicating crown distal tipping, which was validated by meta-analysis (U6-PP angle: 2.19° [1.06°, 3.33°]). In addition, intra-arch anchorage loss was observed at the post-distalization time point (U1 protrusion: 0.39 mm [0.27 mm, 0.51 mm]), which was corrected at the post-treatment time point (incisal edge-PTV distance: -1.50 mm [-2.61 mm, -0.39 mm]).
conclusionAbout 2 mm maxillary molar distalization can be achieved with the sequential distalization protocol, accompanied by slight molar crown distal tipping. Additional studies on this topic are needed due to the high risk of bias in currently available studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.