Evidence map›Paper›PMID 38921448›Full record

ArticleMetabolites2024

Utilising a Clinical Metabolomics LC-MS Study to Determine the Integrity of Biological Samples for Statistical Modelling after Long Term -80 °C Storage: A TOFI_Asia Sub-Study.

Aidan Joblin-Mills, Zhanxuan E Wu, Ivana R Sequeira-Bisson, Jennifer L Miles-Chan, Sally D Poppitt, Karl Fraser

Abstract read
In one paragraph

Article in Metabolites, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aidan Joblin-MillsFood Chemistry & Structure Team, AgResearch, Palmerston North 4410, New Zealand.ORCID 0009-0000-8702-5523
Zhanxuan E WuFood Chemistry & Structure Team, AgResearch, Palmerston North 4410, New Zealand.ORCID 0000-0003-1896-0221
Ivana R Sequeira-BissonHigh-Value Nutrition National Science Challenge, Auckland 1145, New Zealand.ORCID 0000-0001-5414-9925
Jennifer L Miles-ChanHigh-Value Nutrition National Science Challenge, Auckland 1145, New Zealand.ORCID 0000-0003-0313-7048
Sally D PoppittHigh-Value Nutrition National Science Challenge, Auckland 1145, New Zealand.ORCID 0000-0002-2214-8378
Karl FraserFood Chemistry & Structure Team, AgResearch, Palmerston North 4410, New Zealand.ORCID 0000-0002-1136-4024

Funding

Ministry of Business, Innovation and Employment 3710040
6 · The paper itself

Abstract

Biological samples of lipids and metabolites degrade after extensive years in -80 °C storage. We aimed to determine if associated multivariate models are also impacted. Prior TOFI_Asia metabolomics studies from our laboratory established multivariate models of metabolic risks associated with ethnic diversity. Therefore, to compare multivariate modelling degradation after years of -80 °C storage, we selected a subset of aged (≥5-years) plasma samples from the TOFI_Asia study to re-analyze via untargeted LC-MS metabolomics. Samples from European Caucasian (

Indexed as

−80 °C storagecomparisonconfusion matricesethnicityfrozenlipidomicsmetabolomicsmultivariate modellingpredictions

Identifiers

PMID38921448
PMCPMC11205627

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.