Evidence map›Paper›PMID 38921319›Full record

ArticleHealthcare (Basel, Switzerland)2024

Lymphocyte-to-Red Blood Cell Ratio-The Guide Star of Acute Coronary Syndrome Prognosis.

Cosmina Elena Jercălău, Cătălina Liliana Andrei, Lavinia Nicoleta Brezeanu, Roxana Oana Darabont, Suzana Guberna, Andreea Catană, Maria Diana Lungu, Octavian Ceban, Crina Julieta Sinescu

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cosmina Elena JercălăuDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.ORCID 0000-0003-3290-2730
Cătălina Liliana AndreiDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.
Lavinia Nicoleta BrezeanuDepartment of Anaesthesia and Intensive Care, Fundeni Clinical Institute, 022328 Bucharest, Romania.ORCID 0009-0002-2251-0725
Roxana Oana DarabontDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.
Suzana GubernaDepartment of Cardiology, Emergency Hospital "Bagdasar-Arseni", 050474 Bucharest, Romania.
Andreea CatanăDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.ORCID 0000-0003-1628-2949
Maria Diana LunguDepartment of Cardiology, Emergency Hospital "Bagdasar-Arseni", 050474 Bucharest, Romania.
Octavian CebanEconomic Cybernetics and Informatics Department, The Bucharest University of Economic Studies, 010374 Bucharest, Romania.ORCID 0000-0003-3439-3247
Crina Julieta SinescuDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.ORCID 0000-0001-5933-8549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBeneath the surface of the acute ST-elevation myocardial infarction (STEMI) iceberg lies a hidden peril, obscured by the well-known cardiovascular risk factors that tip the iceberg. Before delving into the potential time bomb these risk factors represent, it is crucial to recognize the obscured danger lurking under the surface. What secrets does the STEMI iceberg hold? To unveil these mysteries, a closer look at the pathophysiology of STEMI is imperative. Inflammation, the catalyst of the STEMI cascade, sets off a chain reaction within the cardiovascular system. Surprisingly, the intricate interplay between red blood cells (RBC) and lymphocytes remains largely unexplored in previous research. MATERIALS AND

methodsThe study encompassed 163 patients diagnosed with STEMI. Utilizing linear and logistic regression, the lymphocyte-to-red blood cell ratio (LRR) was scrutinized as a potential predictive biomarker.

resultsThere was a statistically significant correlation between LRR and the prognosis of STEMI patients. Building upon this discovery, an innovative scoring system was proposed that integrates LRR as a crucial parameter.

conclusionsUncovering novel predictive markers for both immediate and delayed complications in STEMI is paramount. These markers have the potential to revolutionize treatment strategies by tailoring them to individual risk profiles, ultimately enhancing patient outcomes.

Indexed as

atherosclerosisinflammationmyocardial infarctionpreventionprognosisrisk profile

Identifiers

PMID38921319
PMCPMC11203887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.