Evidence map›Paper›PMID 38921220›Full record

ArticleBiomimetics (Basel, Switzerland)2024

Octopus-Inspired Soft Robot for Slow Drug Release.

Dingwen Tong, Yiqun Zhao, Zhengnan Wu, Yutan Chen, Xinmiao Xu, Qinkai Chen, Xinjian Fan, Zhan Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dingwen TongSchool of Mechanical and Electrical Engineering, Soochow University, Suzhou 215131, China.
Yiqun ZhaoSchool of Mechanical and Electrical Engineering, Soochow University, Suzhou 215131, China.
Zhengnan WuSchool of Mechanical and Electrical Engineering, Soochow University, Suzhou 215131, China.
Yutan ChenSchool of Future Science and Engineering, Soochow University, Suzhou 215222, China.
Xinmiao XuSchool of Future Science and Engineering, Soochow University, Suzhou 215222, China.
Qinkai ChenSchool of Mechanical and Electrical Engineering, Soochow University, Suzhou 215131, China.
Xinjian FanSchool of Mechanical and Electrical Engineering, Soochow University, Suzhou 215131, China.
Zhan YangSchool of Mechanical and Electrical Engineering, Soochow University, Suzhou 215131, China.

Funding

National Natural Science Foundation of China 61925304National Natural Science Foundation of China 62103294Natural Science Foundation of Jiangsu province BK20210717State Key Laboratory of Robotics and System SKLRS-2023-KF-21
6 · The paper itself

Abstract

Octopus tentacles are equipped with numerous suckers, wherein the muscles contract and expel air, creating a pressure difference. Subsequently, when the muscular tension is released, objects can be securely adhered to. This mechanism has been widely employed in the development of adhesive systems. However, most existing octopus-inspired structures are passive and static, lacking dynamic and controllable adhesive switching capabilities and excellent locomotion performance. Here, we present an octopus-inspired soft robot (OISR). Attracted by the magnetic gradient field, the suction cup structure inside the OISR can generate a strong adsorption force, producing dynamically controllable adsorption and separation in the gastrointestinal (GI) tract. The experimental results show that the OISR has a variety of controllable locomotion behaviors, including quick scrolling and rolling motions, generating fast locomotion responses, rolling over gastric folds, and tumbling and swimming inside liquids. By carrying drugs that are absorbable by GI epithelial cells to target areas, the OISR enables continuous drug delivery at lesions or inflamed regions of the GI tract. This research may be a potential approach for achieving localized slow drug release within the GI tract.

Indexed as

drug deliverymagnetic actuationmultimodal locomotionoctopus-inspiredsoft robotsuction cup

Identifiers

PMID38921220
PMCPMC11202092

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.