Evidence map›Paper›PMID 38920917›Full record

ArticleGels (Basel, Switzerland)2024

Development of an Emulgel for the Effective Treatment of Atopic Dermatitis: Biocompatibility and Clinical Investigation.

Almudena Gómez-Farto, Ana Leticia Jiménez-Escobar, Noelia Pérez-González, Herminia Castán, Beatriz Clares, Salvador Arias-Santiago, Trinidad Montero-Vílchez

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Almudena Gómez-FartoInstituto de Investigación Biotecnológica, Farmacéutica y Medicamentos Huérfanos, S.L, 18016 Granada, Spain.ORCID 0000-0002-9084-050X
Ana Leticia Jiménez-EscobarInstituto de Investigación Biotecnológica, Farmacéutica y Medicamentos Huérfanos, S.L, 18016 Granada, Spain.ORCID 0000-0002-4798-0822
Noelia Pérez-GonzálezInstituto de Investigación Biotecnológica, Farmacéutica y Medicamentos Huérfanos, S.L, 18016 Granada, Spain.ORCID 0000-0001-6251-1752
Herminia CastánInstituto de Investigación Biotecnológica, Farmacéutica y Medicamentos Huérfanos, S.L, 18016 Granada, Spain.ORCID 0000-0002-5055-6934
Beatriz ClaresDepartment of Pharmacy & Pharmaceutical Technology, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-6126-7890
Salvador Arias-SantiagoBiosanitary Institute of Granada (ibs.GRANADA), 18012 Granada, Spain.ORCID 0000-0002-4186-1435
Trinidad Montero-VílchezBiosanitary Institute of Granada (ibs.GRANADA), 18012 Granada, Spain.

Funding

Centre for the Development of Industrial Technology (Spain) 00111667 / ITC-20181113
6 · The paper itself

Abstract

Atopic dermatitis (AD) is a common dermatological disease affecting both children and adults. No drug-free emulgel has been developed and studied in vitro and in vivo for the treatment of AD. The aim of this study was to develop and assess the efficacy of a topical emulgel containing hyaluronic acid, glycerol, Calendula officinalis, Aloe vera, polyphenols and EGF for the concomitant treatment in patients with AD aged over 14. Objective skin barrier function parameters were included, such as transepidermal water loss (TEWL), skin temperature, pH, stratum corneum hydration, skin elasticity and erythema. The subjective opinion of the patients was determined including acceptability, absorption, comfort of use and tolerability, as well as the degree of improvement in patients' quality of life. We observed an improvement in the subjective parameters studied and statistically significant differences in the objective parameters. Specifically, we found an improvement in TEWL (

Indexed as

atopic dermatitisEGFemulgelhyaluronic acid

Identifiers

PMID38920917
PMCPMC11202525

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.