Evidence map›Paper›PMID 38920852›Full record

ArticleDentistry journal2024

Histological In Vivo Evaluation of Intense Pulsed Light Technology: Assessing the Safety on Oral Soft and Hard Tissues.

Yaniv Mayer, Amit Shenhav, Amin Younis, Eran Gabay, Hadar Giladi Zigdon

Abstract read
In one paragraph

Article in Dentistry journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaniv MayerDepartment of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa 3525408, Israel.ORCID 0000-0001-5500-7961
Amit ShenhavThe Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa 3200003, Israel.ORCID 0009-0002-2485-7589
Amin YounisDepartment of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa 3525408, Israel.
Eran GabayDepartment of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa 3525408, Israel.ORCID 0000-0003-0429-2883
Hadar Giladi ZigdonDepartment of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa 3525408, Israel.

Funding

Lumenis (Israel) 0000
6 · The paper itself

Abstract

Intense pulsed light (IPL) is used for aesthetic and therapeutic purposes. According to recent literature, utilizing IPL may boost upregulation of anti-inflammatory cytokines, and downregulation of pro-inflammatory cytokines. Concerns have been raised about potential thermal damage to the soft and hard tissues in the oral cavity. Therefore, the aim of this study was to determine the safety of using IPL of various intensities in the tissues of the oral cavity.

methodsThree adult pigs were included in the trial. The oral cavity was divided into four quadrants and projected with a wide range of IPL settings. Alveolar bone, buccal mucosa, and gingival tissue samples were taken immediately and after 24 h. In each animal, one quadrant of the jaw was left untreated and served as a control. All samples were processed and stained with H&E.

resultsClinical examination showed no evidence of changes in the integrity of the examined tissues. Histological examination of the different tissues did not demonstrate significant thermal damage or changes in the characterization of the cells compared to the control tissues.

conclusionsThe use of IPL in the oral cavity is safe and does not negatively affect the tissues.

Indexed as

histological responseintense pulsed lightoral biopsythermal damage

Identifiers

PMID38920852
PMCPMC11203226

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.