Evidence map›Paper›PMID 38920799›Full record

ArticleBehavioral sciences (Basel, Switzerland)2024

Longitudinal Association between Stressful Life Events and Suicidal Ideation in Adults with Major Depression Disorder: The Mediating Effects of Insomnia Symptoms.

Ya Chen, Xue Han, Yingchen Jiang, Yunbin Jiang, Xinyu Huang, Wanxin Wang, Lan Guo, Ruirui Xia, Yuhua Liao, Huimin Zhang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Behavioral sciences (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ya ChenDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Xue HanDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, China.
Yingchen JiangDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Yunbin JiangDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Xinyu HuangDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Wanxin WangDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Lan GuoDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0002-5213-2158
Ruirui XiaDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, China.
Yuhua LiaoDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, China.
Huimin ZhangDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, China.
Kayla M TeopizBrain and Cognition Discovery Foundation, Toronto, ON M2J 4A6, Canada.
Roger S McIntyreBrain and Cognition Discovery Foundation, Toronto, ON M2J 4A6, Canada.
Beifang FanDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, China.
Ciyong LuDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.

Funding

National Natural Science Foundation of China 81761128030National Natural Science Foundation of China 82373660Sanming Project of Medicine in Shenzhen Nanshan 11
6 · The paper itself

Abstract

Stressful life events (SLEs) and suicidal ideation (SI) are prevalent in persons with major depression disorder (MDD). Less is known about the underlying role of insomnia symptoms in the association between SLEs and SI. This three-wave prospective cohort study sought to investigate the longitudinal association among SLEs, insomnia symptoms, and SI in persons with MDD. The study population included 511 persons with MDD (mean [SD] age, 28.7 [6.7] years; 67.1% were females). Generalized estimated equations (GEEs) were utilized to explore prospective association among exposure of SLEs, insomnia symptoms, and SI. Additionally, a structural equation model (SEM) was employed to estimate the longitudinal mediating effect of insomnia symptoms in the relationship between SLEs and SI. Our study demonstrated that cumulative SLEs were determined to be longitudinally associated with SI in persons with MDD. We further observed that the association between SLEs and SI was significantly mediated by insomnia symptoms. Clinicians assessing persons with MDD, especially those with the history of SLE, could carefully evaluate and promptly treat insomnia symptoms as part of personalized assessment of their depressive illness, thereby achieving early prevention and intervention for suicidal behaviors in persons with MDD.

Indexed as

insomniamajor depression disordermortalitystressful life eventssuicidality

Identifiers

PMID38920799
PMCPMC11200868

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.