Evidence map›Paper›PMID 38920678›Full record

ArticleCells2024

Cardiac Development Long Non-Coding RNA (

Isabela T Pereira, Rubens Gomes-Júnior, Aruana Hansel-Frose, Rhaíza S V França, Man Liu, Hossam A N Soliman, Sunny S K Chan, Samuel C Dudley, Michael Kyba, Bruno Dallagiovanna

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isabela T PereiraBasic Stem Cell Biology Laboratory, Instituto Carlos Chagas-FIOCRUZ-PR, Curitiba 81350-010, PR, Brazil.ORCID 0000-0001-8951-9965
Rubens Gomes-JúniorBasic Stem Cell Biology Laboratory, Instituto Carlos Chagas-FIOCRUZ-PR, Curitiba 81350-010, PR, Brazil.ORCID 0000-0002-7714-5094
Aruana Hansel-FroseBasic Stem Cell Biology Laboratory, Instituto Carlos Chagas-FIOCRUZ-PR, Curitiba 81350-010, PR, Brazil.ORCID 0000-0002-1133-7464
Rhaíza S V FrançaBasic Stem Cell Biology Laboratory, Instituto Carlos Chagas-FIOCRUZ-PR, Curitiba 81350-010, PR, Brazil.ORCID 0009-0000-0557-1417
Man LiuDepartment of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-1390-7862
Hossam A N SolimanLillehei Heart Institute, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-9466-0012
Sunny S K ChanLillehei Heart Institute, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-1432-7381
Samuel C DudleyDepartment of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-5843-5961
Michael KybaLillehei Heart Institute, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-5579-7534
Bruno DallagiovannaBasic Stem Cell Biology Laboratory, Instituto Carlos Chagas-FIOCRUZ-PR, Curitiba 81350-010, PR, Brazil.ORCID 0000-0001-6992-7048

Funding

Unfolded Protein Response and ArrhythmiasR01HL134791 · NHLBI · UNIVERSITY OF MINNESOTA · PI DUDLEY, SAMUEL C · 2017 to 2020
$1.8M
Magnesium, mitochondria, and diastolic dysfunctionR56HL162208 · NHLBI · UNIVERSITY OF MINNESOTA · PI DUDLEY, SAMUEL C · 2022 to 2022
$544k
Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.136364/2017-00National Council for Scientific and Technological Development 442353/2019-7National Council for Scientific and Technological Development 465656/2014-5NIH HHS 1R56HL162208NIH HHS R01-HL134791
6 · The paper itself

Abstract

Successful heart development depends on the careful orchestration of a network of transcription factors and signaling pathways. In recent years, in vitro cardiac differentiation using human pluripotent stem cells (hPSCs) has been used to uncover the intricate gene-network regulation involved in the proper formation and function of the human heart. Here, we searched for uncharacterized cardiac-development genes by combining a temporal evaluation of human cardiac specification in vitro with an analysis of gene expression in fetal and adult heart tissue. We discovered that

Indexed as

Cell DifferentiationHeartHomeostasisMyocytes, CardiacRNA, Long NoncodingCell LineageGene Expression Regulation, DevelopmentalHumansOrganogenesisPluripotent Stem CellsRNA, Long Noncodingcardiac developmentcardiomyocytesgene expressionlncRNA

Identifiers

PMID38920678
PMCPMC11201801

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.