Evidence map›Paper›PMID 38920612›Full record

ArticleBiosensors2024

Design and Application of Microfluidic Capture Device for Physical-Magnetic Isolation of MCF-7 Circulating Tumor Cells.

Akhilesh Bendre, Derangula Somasekhara, Varalakshmi K Nadumane, Ganesan Sriram, Ramesh S Bilimagga, Mahaveer D Kurkuri

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akhilesh BendreCentre for Research in Functional Materials, JAIN (Deemed-to-be University), Bengaluru 562112, Karnataka, India.
Derangula SomasekharaDepartment of Biotechnology, School of Sciences, JAIN (Deemed-to-be-University), JC Road, 34, 1st Cross Road, Sudharna Nagar, Bengaluru 560027, Karnataka, India.
Varalakshmi K NadumaneDepartment of Biotechnology, School of Sciences, JAIN (Deemed-to-be-University), JC Road, 34, 1st Cross Road, Sudharna Nagar, Bengaluru 560027, Karnataka, India.ORCID 0000-0001-9979-5007
Ganesan SriramSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Ramesh S BilimaggaDepartment of Minimal Access, GI and Bariatric Surgery, Fortis Hospital, 14, Cunningham Road, Bengaluru 560052, Karnataka, India.
Mahaveer D KurkuriCentre for Research in Functional Materials, JAIN (Deemed-to-be University), Bengaluru 562112, Karnataka, India.ORCID 0000-0003-0284-7259

Funding

Department of Science & Technology DST/BDTD/32/2019Department of Science & Technology DST/TDT/DDP-31/2021Jain University JU/MRP/Univ/3/2022Vision Group on Science and Technology VGST/K-FISTL1/GRD No. 1053/2021-22
6 · The paper itself

Abstract

Circulating tumor cells (CTCs) are a type of cancer cell that spreads from the main tumor to the bloodstream, and they are often the most important among the various entities that can be isolated from the blood. For the diagnosis of cancer, conventional biopsies are often invasive and unreliable, whereas a liquid biopsy, which isolates the affected item from blood or lymph fluid, is a less invasive and effective diagnostic technique. Microfluidic technologies offer a suitable channel for conducting liquid biopsies, and this technology is utilized to extract CTCs in a microfluidic chip by physical and bio-affinity-based techniques. This effort uses functionalized magnetic nanoparticles (MNPs) in a unique microfluidic chip to collect CTCs using a hybrid (physical and bio-affinity-based/guided magnetic) capturing approach with a high capture rate. Accordingly, folic acid-functionalized Fe

Indexed as

Cell SeparationNeoplastic Cells, CirculatingBreast NeoplasmsFemaleHumansLab-On-A-Chip DevicesMagnetite NanoparticlesMCF-7 CellsMicrofluidic Analytical TechniquesMagnetite NanoparticlescaptureCTCsfunctionalized nanoparticlesmicrofluidicsphysical-bio affinity based/guided magnetic isolationsimulation-aided

Identifiers

PMID38920612
PMCPMC11201624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.