ArticlemBio2024
Coordinated adaptation of
Abstract read
In one paragraph
Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Discovery ofmBio · 2026Article
- A Zur-dependent regulatory RNA involved in maintaining zinc homeostasis in Staphylococcus aureus.Nucleic acids research · 2026Article
- Convergent methodologies in prosthetic joint infection research: integrating transdisciplinary approaches to understand and prevent biofilm-driven failure of orthopaedic prostheses.Journal of medical microbiology · 2026Review
- Article
- Overcoming methicillin resistance in Staphylococcus aureus via metal ion disruption of bacterial metabolism.npj antimicrobials and resistance · 2026Article
- Alanine Uptake Is Required to MaintainMicroorganisms · 2026Article
- Metal-independent effects of calprotectin on cocultures ofbioRxiv : the preprint server for biology · 2026Article
- Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing.Nucleic acids research · 2026Article
- Bacterial pathogen spectrum and antimicrobial resistance in positive pus cultures from hospitalized patients at a maternal and child healthcare specialty hospital in Shenzhen, China, 2021-2025.Frontiers in cellular and infection microbiology · 2026Article
- From Fungicide to Phagosome: A One Health View of Copper-Driven Fungal-Bacterial Interactions.Current clinical microbiology reports · 2026Review
- Unraveling proteomic chaos by independent component analysis-ClpX proficiency promotes the iron and oxygen limitation responses ofmSystems · 2025Article
- Calprotectin protectsmSystems · 2025Article
- Article
- Article
- Calprotectin-mediated survival ofmBio · 2025Article
- Metals in the gut: microbial strategies to overcome nutritional immunity in the intestinal tract.Metallomics : integrated biometal science · 2024Review
- Analysis of genetic requirements and nutrient availability forbioRxiv : the preprint server for biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Valeria M Reyes RuizDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-4824-9898
Jeffrey A FreibergVanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Andy WeissDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Erin R GreenDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Mary-Elizabeth JobsonDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Emily FeltonDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Lindsey N ShawDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-0629-8990
Walter J ChazinVanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0001-5094-8105
Funding
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MARY Kay WASHINGTON · 2002 to 2026
$29.9MTRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGYT32ES007028 · NIEHS · VANDERBILT UNIVERSITY · PI F PETER Guengerich, Fiona Edith Harrison · 1985 to 2026
$15.7MHost-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2MVanderbilt Infection Pathogenesis and Epidemiology Research Training ProgramT32AI007474 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KALAMS, SPYROS A · 1995 to 2025
$6.9MInterdisciplinary Training Program in Lung ResearchT32HL094296 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ray Stokes Peebles · 2008 to 2026
$6.3MMolecular mapping of microbial communities at the host-pathogen interface by multi-modal 3-dimensional imaging mass spectrometryR01AI138581 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric P Skaar, Jeffrey M Spraggins · 2018 to 2026
$5.2MDefining the impact of host factors on the molecular architecture and bacterial physiology of Staphylococcus aureus abscessesR01AI145992 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E, SKAAR, ERIC P · 2020 to 2024
$3.8MThe Staphylococcus aureus response to nutrient zinc restriction during infectionR01AI150701 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SKAAR, ERIC P · 2020 to 2024
$2.1MThe Role and Regulation of Extracellular Proteases in Staphylococcus aureusR01AI124458 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI SHAW, LINDSEY NEIL · 2017 to 2020
$1.7MElucidating the mechanisms of antibiotic tolerance in Staphylococcus aureus biofilmsF32AI169905 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FREIBERG, JEFFREY ALEXANDER · 2022 to 2023
$148kDefining the molecular inventory of staphylococcal tissue abscesses and its effects on the host-pathogen interfaceF32AI157215 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEISS, ANDY · 2021 to 2023
$145kAmerican Heart Association (AHA) 18POST33990262Burroughs Wellcome Fund (BWF) Postdoctoral Enrichment Program AwardHHS | National Institutes of Health (NIH) R01 AI101171, R01 AI138581, R01 AI150701, R01 AI145992, R01 AI124458, T32ES007028, F32AI157215, T32 HL094296, T32 AI007474, F32 AI169905Howard Hughes Medical Institute (HHMI) HHMI Hanna GrayNHLBI NIH HHS T32 HL094296NIAID NIH HHS F32 AI157215NIAID NIH HHS F32 AI169905NIAID NIH HHS R01 AI101171NIAID NIH HHS R01 AI124458NIAID NIH HHS R01 AI138581NIAID NIH HHS R01 AI145992NIAID NIH HHS R01 AI150701NIAID NIH HHS T32 AI007474NIDDK NIH HHS P30 DK058404NIEHS NIH HHS T32 ES007028
Abstract
The host protein calprotectin inhibits the growth of a variety of bacterial pathogens through metal sequestration in a process known as "nutritional immunity." IMPORTANCE:
Indexed as
Leukocyte L1 Antigen ComplexStaphylococcal InfectionsStaphylococcus aureusAdaptation, PhysiologicalAnimalsBacterial ProteinsEndopeptidase ClpGene Expression Regulation, BacterialMetalsMiceBacterial ProteinsEndopeptidase ClpLeukocyte L1 Antigen ComplexMetalscalprotectinclpPnutritional immunityStaphylococcus aureus
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.