ArticlemBio2024
Hierarchical determinants in cytotoxic necrotizing factor (CNF) toxins driving Rho G-protein deamidation versus transglutamination.
Nicholas B Handy, Yiting Xu, Damee Moon, Jacob J Sowizral, Eric Moon, Mengfei Ho, Brenda A Wilson
Abstract read
In one paragraphArticle in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Nicholas B HandyDepartment of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0009-0001-2746-7941 Yiting XuDepartment of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Damee MoonDepartment of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Jacob J SowizralDepartment of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Eric MoonDepartment of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Mengfei HoDepartment of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0002-8315-8158 Brenda A WilsonDepartment of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0003-0843-0139 Funding
Dawn M Carlson MD,MPH Research Fellowship for Women in Science FellowshipFrancis M and Harlie M Clark Research Award FellowshipJenner Family Research Fellowship FellowshipProfessor Alice Carlene Helm Scholarship Award ScholarshipResearch Board of the University of Illinois at Urbana-Champaign RB#18122
6 · The paper itselfAbstract
The cytotoxic necrotizing factor (CNF) family of AB-type bacterial protein toxins catalyze two types of modification on their Rho GTPase substrates: deamidation and transglutamination. It has been established that
Indexed as
Bacterial ToxinsEscherichia coliEscherichia coli ProteinsHEK293 CellsHumansrho GTP-Binding ProteinsBacterial Toxinscytotoxic necrotizing factor type 1Escherichia coli Proteinsrho GTP-Binding Proteinsbacterial toxinenzyme reactionEscherichia coliG proteinsmammalian signalingprotein structure-functionsubstrate specificitytoxin evolution
Identifiers
PMID38920360
PMCPMC11253639
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