Evidence map›Paper›PMID 38920060›Full record

ReviewJournal of the Royal Society, Interface2024

Review of factors affecting virus inactivation in aerosols and droplets.

Alexandra K Longest, Nicole C Rockey, Seema S Lakdawala, Linsey C Marr

Abstract readReview
In one paragraph

Review in Journal of the Royal Society, Interface, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. A look into the virosphere of clouds: A world yet to be explored.Current research in microbial sciences · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Ultrathin water layers on mannosylated gold nanoparticles.Beilstein journal of nanotechnology · 2025
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexandra K LongestDepartment of Civil and Environmental Engineering, Virginia Tech , Blacksburg, VA, USA.ORCID 0000-0001-8463-7532
Nicole C RockeyDepartment of Civil and Environmental Engineering, Duke University , Durham, NC, USA.
Seema S LakdawalaDepartment of Microbiology and Immunology, Emory University , Atlanta, GA, USA.
Linsey C MarrDepartment of Civil and Environmental Engineering, Virginia Tech , Blacksburg, VA, USA.ORCID 0000-0003-3628-6891

Funding

Flu Lab
6 · The paper itself

Abstract

The inactivation of viruses in aerosol particles (aerosols) and droplets depends on many factors, but the precise mechanisms of inactivation are not known. The system involves complex physical and biochemical interactions. We reviewed the literature to establish current knowledge about these mechanisms and identify knowledge gaps. We identified 168 relevant papers and grouped results by the following factors: virus type and structure, aerosol or droplet size, temperature, relative humidity (RH) and evaporation, chemical composition of the aerosol or droplet, pH and atmospheric composition. These factors influence the dynamic microenvironment surrounding a virion and thus may affect its inactivation. Results indicate that viruses experience biphasic decay as the carrier aerosols or droplets undergo evaporation and equilibrate with the surrounding air, and their final physical state (liquid, semi-solid or solid) depends on RH. Virus stability, RH and temperature are interrelated, but the effects of RH are multifaceted and still not completely understood. Studies on the impact of pH and atmospheric composition on virus stability have raised new questions that require further exploration. The frequent practice of studying virus inactivation in large droplets and culture media may limit our understanding of inactivation mechanisms that are relevant for transmission, so we encourage the use of particles of physiologically relevant size and composition in future research.

Indexed as

AerosolsVirus InactivationHumansHumidityHydrogen-Ion ConcentrationParticle SizeTemperatureVirionAerosolsaerosoldroplethumidityinactivationvirus

Identifiers

PMID38920060
PMCPMC11285516

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.