Evidence map›Paper›PMID 38919774›Full record

ReviewInternational journal of nanomedicine2024

Advancements and Challenges in the Application of Metal-Organic Framework (MOF) Nanocomposites for Tumor Diagnosis and Treatment.

Yingze Hou, Can Zhu, Ge Ban, Zhean Shen, Yingbing Liang, Kun Chen, Chenbo Wang, Heng Shi

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingze HouSchool of Intelligent Medical Engineering, Sanquan College of Xinxiang Medical University, Xinxiang, 453003, People's Republic of China.
Can ZhuDepartment of Urology, The Second Clinical Medical College of Anhui Medical University, Hefei, 230032, People's Republic of China.ORCID 0009-0007-4885-5250
Ge BanSchool of Intelligent Medical Engineering, Sanquan College of Xinxiang Medical University, Xinxiang, 453003, People's Republic of China.
Zhean ShenHeart Center, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310000, People's Republic of China.
Yingbing LiangDepartment of Chemistry and Biotechnology, Graduate School of Engineering Tottori University Koyama-Minami 4-101, Tottori, 680-8552, Japan.ORCID 0000-0002-1755-0303
Kun ChenSchool of Intelligent Medical Engineering, Sanquan College of Xinxiang Medical University, Xinxiang, 453003, People's Republic of China.
Chenbo WangSchool of Intelligent Medical Engineering, Sanquan College of Xinxiang Medical University, Xinxiang, 453003, People's Republic of China.
Heng ShiHeart Center, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoscale metal-organic frameworks (MOFs) offer high biocompatibility, nanomaterial permeability, substantial specific surface area, and well-defined pores. These properties make MOFs valuable in biomedical applications, including biological targeting and drug delivery. They also play a critical role in tumor diagnosis and treatment, including tumor cell targeting, identification, imaging, and therapeutic methods such as drug delivery, photothermal effects, photodynamic therapy, and immunogenic cell death. The diversity of MOFs with different metal centers, organics, and surface modifications underscores their multifaceted contributions to tumor research and treatment. This review is a summary of these roles and mechanisms. The final section of this review summarizes the current state of the field and discusses prospects that may bring MOFs closer to pharmaceutical applications.

Indexed as

Metal-Organic FrameworksNanocompositesNeoplasmsAnimalsAntineoplastic AgentsDrug Delivery SystemsHumansNanomedicinePhotochemotherapyAntineoplastic AgentsMetal-Organic Frameworksdrug deliverymetal-organic frameoncotherapyphotothermal effecttumor immunity

Identifiers

PMID38919774
PMCPMC11198007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.