ArticleIJTLD open2024
Timeliness metrics for screening and preventing TB in household contacts of pulmonary TB patients in Kenya.
Article in IJTLD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Screening and tuberculosis preventive treatment among household contacts of drug-resistant tuberculosis patients: a scoping review.BMC infectious diseases · 2026Article
- Optimization of Case Finding and Preventive Treatment Among Household Contacts of People with Tuberculosis in Zimbabwe.Tropical medicine and infectious disease · 2025Article
- Article
- A year in review - evaluating the launch of IJTLD OPEN.IJTLD open · 2025Article
- TB preventive therapy: uptake and time to initiation during implementation of '7-1-7'.IJTLD open · 2024Article
- Applying 'timeliness' to the screening and prevention of TB in household contacts of pulmonary TB patients.IJTLD open · 2024Article
- Launch ofIJTLD open · 2024Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundThe study assessed whether a "7-1-7" timeliness metric for screening and TB preventive therapy (TPT) could be implemented for household contacts (HHCs) of index patients with bacteriologically confirmed pulmonary TB under routine programmatic settings in Kenya.
methodsA longitudinal cohort study conducted among index patients and their HHCs in 12 health facilities, Kiambu County, Kenya.
resultsBetween January and June 2023, 95% of 508 index patients had their HHCs line-listed within 7 days of initiating anti-TB treatment ("First 7"). In 68% of 1,115 HHCs, screening outcomes were ascertained within 1 day of line-listing ("Next 1"). In 65% of 1,105 HHCs eligible for further evaluation, anti-TB treatment, TPT or a decision for no drugs was made within 7 days of screening ("Second 7"). Altogether, 62% of screened HHCs started TPT during the "7-1-7" period compared with 58% in a historical cohort. Main barriers to TPT uptake were HHCs not consulting clinicians, HHCs being unwilling to initiate TPT and drug shortages. Healthcare workers felt that a timeliness metric was valuable for streamlining HHC management and proposed "3-5-7" as a workable alternative.
conclusionsThe national TB programme must generate awareness about TPT, ensure uninterrupted drug supplies and assess whether the "3-5-7" metric can be operationalised.
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