Evidence map›Paper›PMID 38919407›Full record

ArticleIJTLD open2024

Screening of household contacts for TB infection in Cote d'Ivoire.

R K N'Guessan, D A B Orsot, J M Ahui Brou, N K Bamba, M E Tchoutedjem Mefo, A S Bakayoko

Abstract read
In one paragraph

Article in IJTLD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

R K N'GuessanUnité des Mycobactéries Tuberculeuses et Atypiques, Laboratoire National de Référence de la Tuberculose, Institut Pasteur de Côte d'Ivoire, Abidjan.
D A B OrsotUnité des Mycobactéries Tuberculeuses et Atypiques, Laboratoire National de Référence de la Tuberculose, Institut Pasteur de Côte d'Ivoire, Abidjan.
J M Ahui BrouUnité de formation et de recherche (UFR) des Sciences Médicales Université Felix Houphouët-Boigny Service de Pneumologie Centre Hospitalière Universitaire (CHU) de Cocody.
N K BambaUnité des Mycobactéries Tuberculeuses et Atypiques, Laboratoire National de Référence de la Tuberculose, Institut Pasteur de Côte d'Ivoire, Abidjan.
M E Tchoutedjem MefoProgramme National de Lutte contre la Tuberculose Abidjan.
A S BakayokoUFR des Sciences Médicales Université Felix Houphouët-Boigny Service de Pneumologie CHU de Treichville, Abidjan, Côte d'Ivoire.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingCôte d'Ivoire is a country with a high incidence of TB. The control of TB infection is focused on high-risk patients but has limited implementation.

objectiveCost-benefit analysis of TB infection (TBI) screening of household contacts in Côte d'Ivoire to evaluate economic implications of the implementation of interferon-gamma release assays (IGRAs) and the tuberculin skin test (TST).

designWe compared the effectiveness of QuantiFERON-TB Gold Plus (QuantiFERON) with the TST using an economic model previously evaluated in medium TB incidence settings. Principal outcomes relating to TBI screening, as well as the lifetime costs and benefits of the patient cohort, were captured using a decision tree, followed by a Markov model.

resultsQuantiFERON proved to be both more effective and less costly than TST. Compared to QuantiFERON, TST use leads to an approximate 33% increase in the lifetime risk of developing active TB.

conclusionsFor household contacts of active TB cases in Côte d'Ivoire, QuantiFERON is cost-effective when compared with TST.

Indexed as

costslatent tuberculosis infectionQALYsscreening

Identifiers

PMID38919407
PMCPMC11189601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.