Evidence map›Paper›PMID 38919079›Full record

ReviewCurrent medicinal chemistry2025

Optical Molecular Probes for Imaging and Early Diagnosis of Acute Kidney Injury.

Junbing He, Zhenzhou Chen, Yao Lin, Qinghua Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junbing HeJieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China.
Zhenzhou ChenJieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China.
Yao LinJieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China.
Qinghua LiuJieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China.ORCID 0000-0002-6385-5482

Funding

National Natural Science Foundation of China 82302446Natural Science Foundation of Guangdong Province 2023A1515012477
6 · The paper itself

Abstract

The kidneys play an irreplaceable role in metabolism and excretion. However, Acute Kidney Injury (AKI) often occurs due to high local concentrations of drugs, inflammation, and trauma. Activated optical probes with excellent detection performance can effectively identify biomarkers in the initial stage of AKI and play an important role in evaluating AKI and preventing the development of diseases. This article summarizes representative design strategies for molecular probes and special diagnostic applications. These molecular probes show great potential in basic research and clinical diagnosis, enabling enhanced images of tissue structure and biomarkers, as well as early diagnosis of AKI. In addition, the difficulties and challenges that optical probes may face in the development and application of AKI are also discussed in this article.

Indexed as

Acute Kidney InjuryFluorescent DyesMolecular ProbesOptical ImagingAnimalsBiomarkersEarly DiagnosisHumansBiomarkersFluorescent DyesMolecular ProbesAcute kidney injurybiomarkerdiagnosishypoxiaischemia.optical molecular probes

Identifiers

PMID38919079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.