Evidence map›Paper›PMID 38918977›Full record

ArticleCurrent pharmaceutical biotechnology2025

Cardioprotective Potential of

Ebtesam A Mohamad, Samya Mahmoud Ahmed, Marwa A Masoud, Fatma Adel Mohamed, Haitham S Mohammed

Abstract read
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In one paragraph

Article in Current pharmaceutical biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Effects ofAnimals : an open access journal from MDPI · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Pera orange juice (Heliyon · 2024
    Article
  8. Effects ofJournal of oral biology and craniofacial research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ebtesam A MohamadRadiology and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam Bin Abdul-Aziz University, Al-Kharj 11942, Saudi Arabia.ORCID 0000-0001-5296-896X
Samya Mahmoud AhmedBiochemistry Departement, National Organization for Drug Control and Research (NODCAR), Egyptian Drug Authority (EDA), Giza, Egypt.
Marwa A MasoudPharmacology Department, National Organization for Drug Control and Research (NODCAR), Egyptian Drug Authority (EDA), Giza, Egypt.
Fatma Adel MohamedBiophysics Department, Faculty of Science, Cairo University, Cairo, Egypt.
Haitham S MohammedBiophysics Department, Faculty of Science, Cairo University, Cairo, Egypt.

Funding

Prince Sattam bin Abdulaziz University, Saudi Arabia PSAU/2023/01/26639
6 · The paper itself

Abstract

introductionDoxorubicin (DOX) is one of the most potent anticancer drugs that has ubiquitous usage in oncology; however, its marked adverse effects, such as cardiotoxicity, are still a major clinical issue. Plant extracts have shown cardioprotective effects and reduced the risk of cardiovascular diseases.

methodThe current study is intended to explore the cardioprotective effect of ethanolic

resultsIt is concluded that pre and co-treatment with MOE-NIO could protect the heart against DOX-induced cardiotoxicity by suppressing numerous pathways including oxidative stress, inflammation, and apoptosis and by the elevation of tissue antioxidant status.

conclusionThus, it may be reasonable to suggest that pre and co-treatment with MOE-NIO can provide a potential cardioprotective effect when doxorubicin is used in the management of carcinoma.

Indexed as

Cardiotonic AgentsCardiotoxicityDoxorubicinMoringa oleiferaNanoparticlesPlant ExtractsAnimalsAntibiotics, AntineoplasticHeartLiposomesMaleOxidative StressPlant LeavesRatsRats, WistarAntibiotics, AntineoplasticCardiotonic AgentsDoxorubicinLiposomesPlant ExtractsapoptosisCardiotoxicitydoxorubicininflammationMoringa oleiferaoxidative stresssignaling pathways.

Identifiers

PMID38918977

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.