Evidence map›Paper›PMID 38918936›Full record

ArticleJournal of the American Society for Mass Spectrometry2024

Communicating Mass Spectrometry Quality Information in mzQC with Python, R, and Java.

Chris Bielow, Nils Hoffmann, David Jimenez-Morales, Tim Van Den Bossche, Juan Antonio Vizcaíno, David L Tabb, Wout Bittremieux, Mathias Walzer

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. What Have Data Standards Ever Done for Us?Molecular & cellular proteomics : MCP · 2025
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chris BielowBioinformatics Solution Center, Institut für Mathematik und Informatik, Freie Universität Berlin, Takustrasse 9, 14195 Berlin, Germany.ORCID 0000-0001-5756-3988
Nils HoffmannInstitute for Bio- and Geosciences (IBG-5), Forschungszentrum Jülich GmbH, 52428 Jülich, Germany.ORCID 0000-0002-6540-6875
David Jimenez-MoralesDepartment of Medicine, Stanford University School of Medicine, Stanford, California 94305, United States.
Tim Van Den BosscheDepartment of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Technologiepark-Zwijnaarde 75, 9052 Ghent, Belgium.ORCID 0000-0002-5916-2587
Juan Antonio VizcaínoEuropean Molecular Biology Laboratory, EMBL-European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge CB10 1SD, United Kingdom.ORCID 0000-0002-3905-4335
David L TabbEuropean Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen 9713 AV, The Netherlands.ORCID 0000-0001-7223-578X
Wout BittremieuxDepartment of Computer Science, University of Antwerp, Antwerpen 2020, Belgium.ORCID 0000-0002-3105-1359
Mathias WalzerEuropean Molecular Biology Laboratory, EMBL-European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge CB10 1SD, United Kingdom.ORCID 0000-0003-4538-2754

Funding

Wellcome Trust
6 · The paper itself

Abstract

Mass spectrometry is a powerful technique for analyzing molecules in complex biological samples. However, inter- and intralaboratory variability and bias can affect the data due to various factors, including sample handling and preparation, instrument calibration and performance, and data acquisition and processing. To address this issue, the Quality Control (QC) working group of the Human Proteome Organization's Proteomics Standards Initiative has established the standard mzQC file format for reporting and exchanging information relating to data quality. mzQC is based on the JavaScript Object Notation (JSON) format and provides a lightweight yet versatile file format that can be easily implemented in software. Here, we present open-source software libraries to process mzQC data in three programming languages: Python, using pymzqc; R, using rmzqc; and Java, using jmzqc. The libraries follow a common data model and provide shared functionalities, including the (de)serialization and validation of mzQC files. We demonstrate use of the software libraries in a workflow for extracting, analyzing, and visualizing QC metrics from different sources. Additionally, we show how these libraries can be integrated with each other, with existing software tools, and in automated workflows for the QC of mass spectrometry data. All software libraries are available as open source under the MS-Quality-Hub organization on GitHub (https://github.com/MS-Quality-Hub).

Indexed as

Mass SpectrometryProgramming LanguagesProteomicsQuality ControlSoftwareHumansWorkflow

Identifiers

PMID38918936
PMCPMC11311537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.