Evidence map›Paper›PMID 38918790›Full record

ArticleAIDS research and therapy2024

Completion of tuberculosis preventive therapy and associated factors among clients on antiretroviral therapy at Debre Berhan town health facilities, North Shoa Zone, Ethiopia.

Alebachew Zewdu Tegegnework, Muluken Tessema Aemiro, Awraris Hailu Bilchut, Abinet Dagnaw Mekuria, Sisay Shewasinad Yehualashet

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Article in AIDS research and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alebachew Zewdu Tegegnework *HIV/AIDS Care Unit, Debre Berhan comprehensive Specialized Hospital, Amhara Regional State, Debre Berhan, Ethiopia. alebachewzewdu21@gmail.com.
Muluken Tessema Aemiro *School of Public Health, Asrat Woldeyes Health Science Campus, Debre Birhan University, Debre Birhan, Amhara Regional State, Debre Berhan, Ethiopia. mklitmuluken@gmail.com.
Awraris Hailu Bilchut *School of Public Health, Asrat Woldeyes Health Science Campus, Debre Birhan University, Debre Birhan, Amhara Regional State, Debre Berhan, Ethiopia.
Abinet Dagnaw Mekuria *School of Public Health, Asrat Woldeyes Health Science Campus, Debre Birhan University, Debre Birhan, Amhara Regional State, Debre Berhan, Ethiopia.
Sisay Shewasinad Yehualashet *School of Nursing and Midwifery, Department of Paediatrics and Child Health Nursing, Debre Birhan University, Asrat Woldeyes Health Science Campus, Debre Birhan, Amhara Regional State, Debre Berhan, Ethiopia. sisyehu@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis preventive therapy is vital in caring for HIV-positive individuals, as it prevents the progression from latent tuberculosis infection to tuberculosis disease. The aim of the study is to assess the completion of tuberculosis preventive therapy and associated factors among clients receiving antiretroviral therapy in Debre Berhan town, Ethiopia, in 2022.

methodInstitutional based cross sectional study was conducted. Random sampling methods were used to select both study participants and health facilities. Both bivariate and multivariate logistic regression analyses were performed. P-values less than 0.05 were statistically significant.

resultThe study found that, 83% of participants were completed tuberculosis preventive therapy. Completed tuberculosis preventive therapy was associated with no adverse drug events, taking first-line ART, and good ART adherence.

conclusionAccording to the Ethiopian ART guidelines, the study found a low completion rate of tuberculosis preventive therapy among HIV-positive clients on antiretroviral therapy. Factors like no adverse drug events, first-line antiretroviral regimen, and good adherence were significantly associated with completing tuberculosis preventive therapy.

Indexed as

Antitubercular AgentsDrug MonitoringHIV InfectionsTuberculosisAdolescentAdultAnti-HIV AgentsCross-Sectional StudiesEthiopiaFemaleHealth FacilitiesHumansMaleMiddle AgedYoung AdultAnti-HIV AgentsAntitubercular AgentsAntiretroviral therapyAssociated factorsCompletion rateDebre Berhan townEthiopiaNorth Shoa ZoneTuberculosis preventive therapy

Identifiers

PMID38918790
PMCPMC11197169

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