Evidence map›Paper›PMID 38918701›Full record

ArticleBMC genomics2024

ALKBH5 regulates chicken adipogenesis by mediating LCAT mRNA stability depending on m

Xiaohuan Chao, Lijin Guo, Chutian Ye, Aijun Liu, Xiaomeng Wang, Mao Ye, Zhexia Fan, Kang Luan, Jiahao Chen, Chunlei Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. NPoultry science · 2026
    Review
  3. Review
  4. NBiomolecules · 2026
    Review
  5. MFrontiers in genetics · 2026
    Review
  6. Article
  7. Structural Analysis of the AlkB Family in Poultry.Animals : an open access journal from MDPI · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiaohuan ChaoState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Lijin GuoState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Chutian YeState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Aijun LiuState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Xiaomeng WangState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Mao YeState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Zhexia FanState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Kang LuanState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Jiahao ChenCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Chunlei ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Manqing LiuState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Bo ZhouCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Xiquan ZhangState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China.
Zhenhui LiState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China. lizhenhui@scau.edu.cn.
Qingbin LuoState Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, China. qbluo@scau.edu.cn.

Funding

Science and Technology Program of Chaozhou City 202101ZD07The National Key R&D Program of China 2021YFD1300100
6 · The paper itself

Abstract

backgroundPrevious studies have demonstrated the role of N6-methyladenosine (m

resultsThe 6 100-day-old female chickens were categorized into high (n = 3) and low-fat chickens (n = 3) based on their abdominal fat ratios, and their abdominal fat tissues were processed for MeRIP-seq and RNA-seq. An integrated analysis of MeRIP-seq and RNA-seq omics data revealed 16 differentially expressed genes associated with to differential m

conclusionsIn conclusion, ALKBH5 mediates RNA stability of LCAT through demethylation and affects chicken adipogenesis. This study provides a theoretical basis for further understanding of RNA methylation regulation in chicken adipogenesis.

Indexed as

AdenosineAdipogenesisAlkB Homolog 5, RNA DemethylaseChickensPhosphatidylcholine-Sterol O-AcyltransferaseRNA StabilityAnimalsFemaleMethylationRNA, MessengerAdenosineAlkB Homolog 5, RNA DemethylaseN-methyladenosinePhosphatidylcholine-Sterol O-AcyltransferaseRNA, MessengerAdipogenesisALKBH5ChickenLCATMeRIP-seqStability

Identifiers

PMID38918701
PMCPMC11197345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.