Evidence map›Paper›PMID 38918583›Full record

SynthesisProstate cancer and prostatic diseases2025

Sexual outcomes in men who have sex with men who underwent radical prostatectomy.

F Vedovo, C Lonati, N Suardi, L Mariani, P Capogrosso, V Ficarra, A Salonia, C Trombetta

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Prostate cancer and prostatic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. New trends on the management of localized prostate cancer.Prostate cancer and prostatic diseases · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

F VedovoDepartment of Medicine, Urological Clinic, Surgery and Health Sciences, University of Trieste, Trieste, Italy. francesca.vedovo@gmail.com.ORCID http://orcid.org/0000-0002-9791-6888
C LonatiDepartment of Medical and Surgical Specialties, Urology Unit, ASST Spedali Civili di Brescia, Radiological Science and Public Health, University of Brescia, Brescia, Italy.
N SuardiDepartment of Medical and Surgical Specialties, Urology Unit, ASST Spedali Civili di Brescia, Radiological Science and Public Health, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0002-4331-3010
L MarianiAST 3, Civitanova Marche, Italy.
P CapogrossoDepartment of Urology and Andrology, Ospedale di Circolo and Macchi Foundation, Varese, Italy.ORCID http://orcid.org/0000-0003-2347-9504
V FicarraGaetano Barresi Department of Human and Paediatric Pathology, Urologic Section, University of Messina, Messina, Italy.
A SaloniaDivision of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID http://orcid.org/0000-0002-0595-7165
C TrombettaDepartment of Medicine, Urological Clinic, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSexual difficulties are a recognized consequence of prostate cancer (PCa) treatments. An estimated one in three men who have sex with men (MSM) receive PCa a diagnosis during their lifetime. MSM may experience all types of sexual dysfunction as reported in men who have sex with women (MSW), along with a number of more specific bothersome problems. This systematic literature review aims to evaluate sexual outcomes in MSM who have undergone radical prostatectomy (RP).

methodsA systematic review was carried out following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The searches were made using relevant keywords in the PubMed, Scopus, and Web of Science databases, thus including the whole literature from January 2000 to November 2023. Studies which did not allow to retrieve data on sexual outcomes on MSM treated with RP for PCa were excluded. Data on sexual outcomes and health-related quality of life (HRQoL) were retrieved, mostly including changes in libido, erectile function, ejaculatory disorders, orgasm, climacturia, changes in role-in-sex identity, changes in sexual partnerships, and the presence of painful receptive anal intercourses (AI). PROSPERO ID: CRD42024502592.

resultsSix articles met the inclusion criteria. In total, data of 260 patients were analyzed. Three main themes emerged: (a) MSM may experience specific sexual dysfunctions due to the different dynamics of their intimacy; (b) the lack of tool validated on gay and bisexual population to assess sexual outcomes (c) the need for a tailored approach that also takes into account sexual orientation throughout the oncological journey.

conclusionsMSM undergoing RP may experience similar sexual problems as MSW. Painful AI should be considered a potential post-operative adverse outcome in MSM. Future studies should prioritize validating a questionnaire that explores AI. Healthcare providers should adopt a tailored approach that takes into account sexual orientation throughout the cancer journey.

Indexed as

Homosexuality, MaleProstatectomyProstatic NeoplasmsSexual BehaviorSexual Dysfunction, PhysiologicalHumansMaleQuality of Life

Identifiers

PMID38918583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.