ReviewJournal of perinatology : official journal of the California Perinatal Association2024
At a crossroads for early medical treatment of persistent patent ductus arteriosus in preterm infants.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Two-Year Outcomes of a Randomized Controlled Trial of Nonintervention Versus Oral Ibuprofen for Patent Ductus Arteriosus in Premature Infants.Journal of Korean medical science · 2026Trial
- Ibuprofen for hemodynamically significant patent ductus arteriosus in extremely preterm infants: a target trial emulation.Translational pediatrics · 2026Article
- PDA in Prematurity: Rethinking a Decades-Old Debate in 2026.Biomedicines · 2026Review
- Artificial intelligence for patent ductus arteriosus-a systematic review.Frontiers in pediatrics · 2026Review
- Patent Ductus Arteriosus Occlusion in the Premature Infant: Persistent Research Gaps.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Reply to letter to the editor: heterogeneity in effects of PDA treatment.European journal of pediatrics · 2025Article
- Letter to the editor: heterogeneity in effects of PDA treatment.European journal of pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Administration of early medical therapy for the patent ductus arteriosus has ebbed and flowed through the years, with a multitude of studies failing to demonstrate a reduction in morbidity or mortality from ductal closure in the preterm population. Concerningly, an increasing number of studies have demonstrated an increase in morbidity, such as bronchopulmonary dysplasia and mortality with the use of early medical therapy to close the ductus. Considering information regarding potential risk without clear benefit in an overall cohort of preterm patients with a patent ductus, use of early medical therapy is increasingly challenging to justify and necessitates studies that will aid in identifying a patient population that would benefit from ductal closure and timing of therapy.
Indexed as
Identifiers
38918573What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.