Evidence map›Paper›PMID 38918567›Full record

ArticleEye (London, England)2024

Relative foveal dark adaptation: a potential method for assessing macular health.

Julia S Kane, Mark Gaspich, Avery Gold, Hillary Pichardo, Steven A Kane

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia S KaneBoston University School of Public Health, Boston, MA, USA.
Mark GaspichUniversity of New Haven, West Haven, CT, USA.
Avery GoldAlbert Einstein College of Medicine, Bronx, NY, USA.
Hillary PichardoCity College, Department of Biology, New York, NY, USA.
Steven A KaneThe Edward S. Harkness Eye Institute, Columbia University, New York, NY, 10032, USA. sak6@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-6489-8185

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveDark adaptation measures photoreceptor recovery following intense light stimulation. Time to recovery reflects retinal function. We describe a novel method of relative foveal dark adaptation using an iPhone. Data from a small number of healthy subjects were studied to assess reproducibility, effects of age, and consider potential clinical utility.

methodsRelative foveal dark adaption was studied in 6 normal subjects across ages from 20 to 81 years and across differing testing conditions. Foveal bleaching is produced by fixating a bright white circle on an iPhone for variable times. After foveal bleaching an annular surround appears to complete a bullseye stimulus with surround initially brighter than centre. As the fovea recovers the centre regains brightness. Relative foveal dark adaptation, the time for the visual anchor to shift from surround to centre, was studied across a range of bleaching times, ages, and testing conditions.

resultsDispersion of dark adaptation times grows with increasing age. Foveal bleaching for 30 s was as effective as longer times. Testing times with a 30 s bleach were less than 1 min. Foveal dark adaptation was reproducible within each subject and was unaffected by ambient room lighting, pupil size, and light attenuation. Repeat, immediately sequential testing was similarly reproducible except after long bleaching.

conclusionsThis method of dark adaptation is intuitive, repeatable, and relatively unaffected by testing condition. Testing times are brief, requiring only an iPhone screen positioned at reading distance. Relative foveal dark adaptation may be a useful tool to assess macular health.

Indexed as

Dark AdaptationFovea CentralisAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPhotic StimulationReproducibility of ResultsSmartphoneVisual AcuityYoung Adult

Identifiers

PMID38918567
PMCPMC11461673

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.