Evidence map›Paper›PMID 38918534›Full record

ArticleNature metabolism2024

The hidden impact of in-source fragmentation in metabolic and chemical mass spectrometry data interpretation.

Martin Giera, Aries Aisporna, Winnie Uritboonthai, Gary Siuzdak

Abstract readLetter
In one paragraph

Article in Nature metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Assessing the metabolomics "dark matter" by a detectable khipu model.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Untargeted Multiple Reaction Monitoring.Analytical chemistry · 2026
    Article
  13. Article
  14. Article
  15. Principles ofbioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martin GieraCenter for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands. M.A.Giera@lumc.nl.ORCID http://orcid.org/0000-0003-1684-1894
Aries AispornaScripps Center of Metabolomics and Mass Spectrometry, La Jolla, CA, USA.
Winnie UritboonthaiScripps Center of Metabolomics and Mass Spectrometry, La Jolla, CA, USA.
Gary SiuzdakScripps Center of Metabolomics and Mass Spectrometry, La Jolla, CA, USA. siuzdak@scripps.edu.ORCID http://orcid.org/0000-0002-4749-0014

Funding

Metabolomics Technologies to Advance Biomedical ResearchR35GM130385 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI GARY E SIUZDAK · 2019 to 2026
$3.9M
NIGMS NIH HHS R35 GM130385Novo Nordisk Fonden (Novo Nordisk Foundation) NNF21CC0073729
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mass SpectrometryHumansMetabolomics

Identifiers

PMID38918534
PMCPMC11826480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.