Evidence map›Paper›PMID 38918405›Full record

ArticleScientific data2024

A multi-omics dataset of the response to early plant polysaccharide ingestion in rabbits.

Charlotte Paës, Martin Beaumont, Thierry Gidenne, Karine Bébin, Joël Duperray, Charly Gohier, Emeline Guené-Grand, Gwénaël Rebours, Adrien Castinel, Céline Barilly and 9 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Charlotte PaësGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France. charlotte.paes@purpan.fr.ORCID 0009-0002-4099-513X
Martin BeaumontGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Thierry GidenneGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Karine BébinCCPA, ZA du Bois de Teillay, 35150, Janzé, France.
Joël DuperrayEVIALIS, Lieu dit Talhouët, 56250, Saint Nolff, France.
Charly GohierMiXscience, 2 avenue de Ker Lann, 35170, Bruz, France.
Emeline Guené-GrandWISIUM, Rue de l'église, BP50019, 02407, Chierry, France.
Gwénaël ReboursTECHNA, Route de St-Étienne-de-Montluc, 44220, Couëron, France.
Adrien CastinelGeT-PlaGe, Genotoul, INRAE, Castanet-Tolosan, 31326, France.
Céline BarillyGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Béatrice GabinaudGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Carole BannelierGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Laure GressGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
François LaperruqueGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Patrick AymardGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Anne-Marie DebrusseGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Laurent CauquilGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Géraldine PascalGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France.
Sylvie CombesGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Paris, Castanet-Tolosan, France. Sylvie.combes@inrae.fr.ORCID 0000-0002-2945-4423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transition from a milk-based diet to exclusive solid feeding deeply modifies microbiota-host crosstalk. Specifically, early ingestion of plant polysaccharides would be one of the main nutritional components to drive host-microbiota-interaction. To capture the effects of polysaccharides early-life nutrition (starch vs rapidly fermentable fiber) on the holobiont development, we investigated on the one hand the gut bacteriome and metabolome and on the other hand the transcriptome of two host gut tissues. Rabbit model was used to study post-natal co-development of the gut microbiota and its host around weaning transition. The assessment of the microbial composition of the gut appendix together with the caecum was provided for the first time. Gene expression signatures were analyzed along the gut (ileum and caecum) through high-throughput qPCR. The data collected were completed by the analysis of animal growth changes and time-series assessment of blood biomarkers. Those accessible and reusable data could help highlight the gut development dynamics as well as biological adaptation processes at the onset of solid feeding.

Indexed as

Gastrointestinal MicrobiomePolysaccharidesAnimalsCecumMetabolomeMultiomicsRabbitsTranscriptomeWeaningPolysaccharides

Identifiers

PMID38918405
PMCPMC11199578

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.