Evidence map›Paper›PMID 38918080›Full record

ReviewACS synthetic biology2024

Toward a Circular Bioeconomy: Designing Microbes and Polymers for Biodegradation.

Vikram Mubayi, Colleen B Ahern, Magdalena Calusinska, Michelle A O'Malley

Erratum issuedAbstract readReview
In one paragraph

Review in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
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  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Vikram MubayiDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.ORCID 0000-0002-6784-5177
Colleen B AhernDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.
Magdalena CalusinskaDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.
Michelle A O'MalleyDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.ORCID 0000-0002-6065-8491

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymer production is rapidly increasing, but there are no large-scale technologies available to effectively mitigate the massive accumulation of these recalcitrant materials. One potential solution is the development of a carbon-neutral polymer life cycle, where microorganisms convert plant biomass to chemicals, which are used to synthesize biodegradable materials that ultimately contribute to the growth of new plants. Realizing a circular carbon life cycle requires the integration of knowledge across microbiology, bioengineering, materials science, and organic chemistry, which itself has hindered large-scale industrial advances. This review addresses the biodegradation status of common synthetic polymers, identifying novel microbes and enzymes capable of metabolizing these recalcitrant materials and engineering approaches to enhance their biodegradation pathways. Design considerations for the next generation of biodegradable polymers are also reviewed, and finally, opportunities to apply findings from lignocellulosic biodegradation to the design and biodegradation of similarly recalcitrant synthetic polymers are discussed.

Indexed as

Biodegradation, EnvironmentalPolymersBacteriaBiomassLigninLigninlignocellulosePolymersbiodegradationcircular plastic life cycledegradable polymersgenetic engineeringlignocellulosemicrobes

Identifiers

PMID38918080
PMCPMC11264326

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.