Evidence map›Paper›PMID 38918065›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Thalamocortical mGlu8 Modulates Dorsal Thalamus Excitatory Transmission and Sensorimotor Activity.

Bretton P Nabit, Anne Taylor, Danny G Winder

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecular pharmacology of mGluMolecular pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bretton P NabitDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee 37203.ORCID 0000-0001-9459-2462
Anne TaylorVanderbilt Center for Addiction Research, Vanderbilt University, Nashville, Tennessee 37203.
Danny G WinderDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee 37203 danny.winder@umassmed.edu.

Funding

Sex Dependent Recruitment of PKCdelta Neurons by Stress: Administrative Supplement for Noradrenergic Regulation in the BNSTR01DA042475 · NIDA · VANDERBILT UNIVERSITY · PI WINDER, DANNY G. · 2016 to 2025
$4.0M
COCAINE: A STUDY OF THE BIOCHEMICAL MECHANISM OF ACTIONR37DA005477 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI CARROLL, FRANK IVY · 1996 to 2007
$3.4M
Design and Development of Pharmacotherapies for Treating Stimulant AbuseR01DA005477 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI CARROLL, FRANK IVY · 1988 to 2010
$955k
NIDA NIH HHS R01 DA005477NIDA NIH HHS R01 DA042475NIDA NIH HHS R37 DA005477
6 · The paper itself

Abstract

Metabotropic glutamate receptor 8 (mGlu8) is a heterogeneously expressed and poorly understood glutamate receptor with potential pharmacological significance. The thalamic reticular nucleus (TRN) is a critical inhibitory modulator of the thalamocortical-corticothalamic (TC-CT) network and plays a crucial role in information processing throughout the brain, is implicated in a variety of psychiatric conditions, and is also a site of significant mGlu8 expression. Using both male and female mice, we determined via fluorescent in situ hybridization that parvalbumin-expressing cells in the TRN core and shell matrices (identified by

Indexed as

Mice, KnockoutReceptors, Metabotropic GlutamateAnimalsCerebral CortexFemaleMaleMiceMice, Inbred C57BLNeural PathwaysParvalbuminsSynaptic TransmissionThalamusmetabotropic glutamate receptor 8ParvalbuminsReceptors, Metabotropic GlutamateelectrophysiologymGlu8mGlu receptorsensorimotor gatingthalamic reticular nucleusthalamocortical system

Identifiers

PMID38918065
PMCPMC11293446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.