Evidence map›Paper›PMID 38918040›Full record

ArticleAmerican journal of epidemiology2025

Ambient exposure to fine particulate matter with oxidative potential affects oxidative stress biomarkers in pregnancy.

Qi Meng, Jonathan Liu, Jiaqi Shen, Irish Del Rosario, Carla Janzen, Sherin U Devaskar, Pascale S J Lakey, Manabu Shiraiwa, Scott Weichenthal, Yifang Zhu and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. PMiScience · 2026
    Review
  2. Article
  3. Uterine Vulnerability to Environmental PMInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qi MengDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, United States.
Jonathan LiuDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California, Los Angeles, CA, United States.
Jiaqi ShenDepartment of Atmospheric & Oceanic Sciences, University of California, Los Angeles, CA, United States.
Irish Del RosarioDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, United States.
Carla JanzenDepartment of Obstetrics & Gynecology, University of California, Los Angeles, CA, United States.
Sherin U DevaskarDepartment of Pediatrics, University of California, Los Angeles, CA, United States.
Pascale S J LakeyDepartment of Chemistry, University of California, Irvine, CA, United States.
Manabu ShiraiwaDepartment of Chemistry, University of California, Irvine, CA, United States.
Scott WeichenthalDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada.
Yifang ZhuDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California, Los Angeles, CA, United States.
Farzan OroumiyehDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California, Los Angeles, CA, United States.
Sudipto BanerjeeDepartment of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA, United States.
Suzanne E PaulsonDepartment of Atmospheric & Oceanic Sciences, University of California, Los Angeles, CA, United States.
Michael JerrettDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California, Los Angeles, CA, United States.
Kimberly C PaulDepartment of Neurology, University of California, Los Angeles, CA, United States.
Beate RitzDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, United States.ORCID 0000-0001-6976-7339

Funding

National Exposure Assessment Laboratory at EmoryU2CES026560 · NIEHS · EMORY UNIVERSITY · PI WALLER, LANCE A · 2015 to 2015
$8.3M
Imaging Innovations for Placental Assessment in Response to Environmental PollutionU01HD087221 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEVASKAR, SHERIN U, JANZEN, CARLA · 2015 to 2015
$4.3M
Electrochemical Liquid Biopsy Assessing Placental HealthR01HD100015 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEVASKAR, SHERIN U, WEI, FANG · 2019 to 2023
$3.2M
Biomarkers and Genes Associated with Placental Development and Function in Response to Environmental PollutionR01HD089714 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEVASKAR, SHERIN U · 2016 to 2020
$3.2M
California Air Resources Board 17RD012National Institute of Environmental Health Sciences of the National Institutes of Health U2CES026560NICHD NIH HHS R01 HD089714NICHD NIH HHS R01 HD100015NICHD NIH HHS U01 HD087221NICHD NIH HHS U01HD087221NIEHS NIH HHS U2C ES026560
6 · The paper itself

Abstract

Prenatal exposures to ambient particulate matter (PM2.5) from traffic may generate oxidative stress and thus contribute to adverse birth outcomes. We investigated whether PM2.5 constituents from brake and tire wear affect levels of oxidative stress biomarkers (malondialdehyde [MDA], 8-hydroxy-2'-deoxyguanosine [8-OHdG]) using urine samples collected up to 3 times during pregnancy in 156 women recruited from antenatal clinics at the University of California Los Angeles. Land use regression models with co-kriging were employed to estimate average residential outdoor concentrations of black carbon (BC), PM2.5 mass, PM2.5 metal components, and 3 PM2.5 oxidative potential metrics during the 4 weeks prior to urine sample collection. The 8-OHdG concentrations in mid-pregnancy increased by 24.8% (95% confidence interval [CI], 9.0-42.8) and 14.3% (95% CI, 0.4%-30.0%) per interquartile range (IQR) increase in PM2.5 mass and BC, respectively. The brake wear marker (barium) and the oxidative potential metrics were associated with increased MDA concentration in the first sample collected (10-17 gestational week), but 95% CIs included the null. Traffic-related air pollution contributed in early to mid-pregnancy to oxidative stress generation previously linked to adverse birth outcomes. This article is part of a Special Collection on Environmental Epidemiology.

Indexed as

Air PollutantsEnvironmental ExposureMaternal ExposureOxidative StressParticulate Matter8-Hydroxy-2'-DeoxyguanosineAdultAir PollutionBiomarkersDeoxyguanosineFemaleHumansLos AngelesMalondialdehydePregnancyVehicle Emissions8-Hydroxy-2'-DeoxyguanosineAir PollutantsBiomarkersDeoxyguanosineMalondialdehydeParticulate MatterVehicle Emissionsfine particulate matteroxidative stresspregnancytraffic related air pollution

Identifiers

PMID38918040
PMCPMC11735968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.