Evidence map›Paper›PMID 38917889›Full record

ArticleJournal of affective disorders2024

Sleep quality predicts future mood symptoms in adolescents with bipolar disorder.

Michelle E Stepan, Peter L Franzen, Giana I Teresi, Noelle Rode, Tina R Goldstein

Abstract read
In one paragraph

Article in Journal of affective disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Childhood Trauma, Perceived Stress, and Developmental Trajectories of Sleep Problems in Adolescents.Stress and health : journal of the International Society for the Investigation of Stress · 2026
    Article
  3. Sleeping Less Than Usual Is Associated With Greater Daily Depression and Higher Reactivity to Negative Interpersonal Events Among Suicidal Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michelle E StepanDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States of America. Electronic address: stepanme@upmc.edu.
Peter L FranzenDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States of America.
Giana I TeresiDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States of America.
Noelle RodeDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States of America.
Tina R GoldsteinDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States of America.

Funding

Translational Research Training in Sleep MedicineT32HL082610 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Daniel J. Buysse, PETER L FRANZEN · 2007 to 2026
$5.8M
Dialectical Behavior Therapy (DBT) for Adolescents with Bipolar DisorderR01MH100056 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOLDSTEIN, TINA R · 2014 to 2019
$4.5M
The Effect of Acoustic Enhancement of Slow-Wave Activity on Cognitive Control and Emotional Reactivity in Young Adults with Anxiety and Depression SymptomsK01MH130502 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Michelle Elizabeth Stepan · 2022 to 2026
$874k
NHLBI NIH HHS T32 HL082610NIMH NIH HHS K01 MH130502NIMH NIH HHS R01 MH100056
6 · The paper itself

Abstract

backgroundPoor sleep is prevalent in adolescents with bipolar disorder, precedes illness onset, and is associated with worse mood symptoms. We examined interrelationships between sleep quality and mood symptoms in adolescents with bipolar disorder, particularly effects of sleep quality on emergent mood symptoms.

methodsAdolescents with bipolar disorder participated in a two-year longitudinal treatment study. Sleep quality (Pittsburgh Sleep Quality Index, PSQI) was assessed quarterly during treatment (baseline, 3-, 6-, 9-, 12-month visits) and twice during follow-up (18-, 24-month visits). Mood symptoms (ALIFE Psychiatric Status Ratings) were retrospectively rated weekly by an independent clinician. Lag models tested whether sleep quality predicted next month's mood symptoms and whether mood symptoms predicted future sleep quality.

resultsAdolescents with bipolar disorder had poor sleep quality. Sleep quality initially improved but remained stable thereafter. Worse sleep quality at 6-months predicted worse depression, hypomania, and suicidal ideation the following month. Sleep quality was worse for adolescents who had a suicide attempt during the study compared to those who did not and was worse preceding months with a suicide attempt compared to months without attempts. Alternatively, worse depression predicted worse future sleep quality at baseline, 3-, and 18-months and worse suicidal ideation predicted worse future sleep quality at baseline, 12-, and 18-months. LIMITATIONS: Mood symptoms were rated retrospectively and the PSQI may not capture all dimensions of sleep important for mood symptoms.

conclusionsTargeted evidence-based sleep treatment in adolescents with bipolar disorder may alleviate sleep problems and have additional benefits on mood symptoms and suicidality risk.

Indexed as

AffectBipolar DisorderSleep QualitySuicidal IdeationSuicide, AttemptedAdolescentDepressionFemaleHumansLongitudinal StudiesMaleManiaRetrospective StudiesSleep Wake DisordersAdolescentsBipolar disorderPittsburgh sleep quality indexSleep qualitySuicidal ideationSuicide attempts

Identifiers

PMID38917889
PMCPMC12208217

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.