Evidence map›Paper›PMID 38917112›Full record

SynthesisPloS one2024

Is Stroke risk analysis (SRA) a reliable method for predicting atrial fibrillation? A systematic review.

Rafael Alessandro Ferreira Gomes, Michel Pompeu Barros de Oliveira Sá, Marcela Vasconcelos Montenegro, Ludmila Cristina Camilo Furtado, José Henrique Cardoso Ferreira da Costa, Daniel Barros Coutinho, Johnnes Henrique Vieira Silva, Dário Celestino Sobral Filho

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Feature Review Papers in Stroke and Cerebrovascular Disease.Journal of cardiovascular development and disease · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rafael Alessandro Ferreira GomesUniversity of Pernambuco, Recife, Pernambuco, Brazil.
Michel Pompeu Barros de Oliveira SáUniversity of Pernambuco, Recife, Pernambuco, Brazil.
Marcela Vasconcelos MontenegroUniversity of Pernambuco, Recife, Pernambuco, Brazil.
Ludmila Cristina Camilo FurtadoUniversity of Pernambuco, Recife, Pernambuco, Brazil.ORCID 0000-0002-5497-4033
José Henrique Cardoso Ferreira da CostaUniversity of Pernambuco, Recife, Pernambuco, Brazil.
Daniel Barros CoutinhoUniversity of Pernambuco, Recife, Pernambuco, Brazil.
Johnnes Henrique Vieira SilvaUniversity of Pernambuco, Recife, Pernambuco, Brazil.ORCID 0000-0003-3329-7237
Dário Celestino Sobral FilhoUniversity of Pernambuco, Recife, Pernambuco, Brazil.ORCID 0000-0002-5301-7741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtrial fibrillation is responsible for a considerable number of cases of cardioembolism, accounting for 17% to 30% of the etiologies of all strokes. The software known as Stroke Risk Analysis (SRA) detects patients at high risk of paroxysmal atrial fibrillation by analyzing a continuous electrocardiogram recorded over different periods of time.

objectivesThis article aims to carry out a systematic review investigating the effectiveness of the SRA method in predicting the risk of stroke patients having paroxysmal atrial fibrillation as the cause of the event.

methodsThe methods correspond to the format of the International Prospective Register of Systematic Reviews Protocol, according to CRD Identification Code: CRD42021253974. A systematic search was carried out in BMJB, PubMed/MEDLINE, Science Direct and LILACS. Six cohort studies met the inclusion criteria, representing a total of 2,088 participants with stroke, and compared the detection of patients with paroxysmal atrial fibrillation on the continuous recording electrocardiogram with a time variation of 1 to 48h with the use of SRA.

resultsStudies have shown that SRA has a high negative predictive value (between 96 and 99.1%) and can contribute to the selection of patients at high risk of paroxysmal atrial fibrillation to be referred for implantable cardiac monitoring to continue the investigation.

conclusionsA sequential combination of SRA with implantable cardiac monitoring is a promising strategy for detecting undiagnosed paroxysmal atrial fibrillation. Thus, the SRA can act as a cost-effective pre-selection tool to identify patients at higher risk of having paroxysmal atrial fibrillation as a possible cause of stroke and who may benefit from implantable cardiac monitoring. However, the lack of randomized studies is a limitation that must be considered.

Indexed as

Atrial FibrillationElectrocardiographyStrokeHumansRisk AssessmentRisk Factors

Identifiers

PMID38917112
PMCPMC11198814

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.