SynthesisPloS one2024
Systematic review and meta-analysis on the prevalence and associated factors of depression among hypertensive patients in Ethiopia.
Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Psychological Burden in Uncontrolled Hypertension: Findings from the ERIDANO Multicenter Study.Journal of clinical medicine · 2026Article
- Effects of occupational factors on depression in Chinese veterans: a fsQCA study based on 2022 CFPS data.Frontiers in psychology · 2026Article
- Construction of a machine learning-based risk prediction model for depression in middle-aged and elderly patients with cardiovascular metabolic diseases in China: a longitudinal study.BMC public health · 2025Article
- The triangulation of multimorbidity: A systematic review of primary sleep disorders, hypertension, and psychiatric disorders.PLOS global public health · 2025Article
- Association between weight-adjusted waist circumference index and depression in older patients with hypertension: a study based on NHANES 2007-2016.Frontiers in public health · 2024Article
- Prevalence and Predictors of Depression Symptoms Among Afghan Hypertensive Patients: Secondary Analysis of a Multi-Center Cross-Sectional Study.Integrated blood pressure control · 2024Article
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Authors and funding
5 authors.
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Abstract
backgroundIdentifying individuals at increased risk for depression allows for earlier intervention and treatment, ultimately leading to better outcomes and potentially preventing severe symptoms. However, to date, no systematic reviews or meta-analyses have estimated the prevalence of depression among hypertensive patients. Thus, this review was initiated to determine the prevalence and factors associated with depression among patients with hypertension in Ethiopia.
methodsMultiple databases, such as PubMed, African Journals Online, the Cochrane Library, and Google Scholar, were used to ensure wider coverage of relevant studies. The data extracted from Microsoft Excel were imported into STATA version 11 (Stata Corp LLC, TX, USA) for further analysis. The pooled prevalence of depression was estimated using a random effects model. To evaluate statistical heterogeneity, the Cochrane Q test and I2 statistic were used.
resultsThe random effect model indicated that the pooled prevalence of depression in 12 studies conducted in Ethiopia was 32.43% (95% CI: 25.18, 39.67%). Being female (POR = 2.41; 95% CI: 1.89, 3.07, I2 = 17.7%, P = 0.302), having comorbid illnesses (POR = 3.80; 95% CI: 2.09, 6.90, I2 = 81%, P = 0.005), having poor blood pressure control (POR = 3.58; 95% CI: 2.51, 5.12, I2 = 0.0%, P = 0.716), having a family history of depression (POR = 3.43; 95% CI: 1.98, 5.96, I2 = 62.6%, P = 0.069), being single (POR = 2.30; 95% CI: 1.35, 3.99, I2 = 48.0%, P = 0.146) and having poor social support (POR = 4.24; 95% CI: 1.29, 13.98, I2 = 95.8%, P<0.001) were positively associated with depression among hypertensive patients.
conclusionOverall, the results of our review showed that depression affects a significant number of Ethiopians who have hypertension. Being female, being single, having comorbidities, having poor blood pressure control, having a family history of depression, and having poor social support were factors associated with depression among patients with hypertension. For those who are depressed, improving the psycho-behavioral treatment linkage with the psychiatric unit can result in improved clinical outcomes.
trial registrationProspero Registration number: CRD42024498447. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024498447.
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