Evidence map›Paper›PMID 38916815›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

The definitions, assessment, and dimensions of cancer-related fatigue: A scoping review.

Kayla F Keane, Jordan Wickstrom, Alicia A Livinski, Catherine Blumhorst, Tzu-Fang Wang, Leorey N Saligan

Abstract readScoping Review
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Cancer-related fatigue in cancer survivors: an updated clinical practice review for healthcare providers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  3. Article
  4. The relationship between the latent profiles of cancer-related fatigue characteristics and exercise adherence in colorectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Development and validation of a machine learning model to predict moderate-to-severe cancer-related fatigue in breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. Article
  7. Current status and influencing factors of cancer-related fatigue in gastric cancer patients undergoing chemotherapy: A cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Biobehavioral correlates of multidimensional fatigue in men with prostate cancer: A secondary data analysis.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2025
    Observational
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kayla F KeaneNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-2639-8662
Jordan WickstromSinai Rehabilitation Center, Sinai Hospital of Baltimore, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-2214-5369
Alicia A LivinskiOffice of Research Services, Office of the Director, National Institutes of Health Library, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-7201-3500
Catherine BlumhorstNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.
Tzu-Fang WangNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.
Leorey N SaliganNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA. saliganl@mail.nih.gov.ORCID http://orcid.org/0000-0001-9481-7836

Funding

Investigating Molecular-Genetic Correlates of FatigueZIANR000019 · NINR · NATIONAL INSTITUTE OF NURSING RESEARCH · PI SALIGAN, LEOREY · 2010 to 2025
$12.8M
6 · The paper itself

Abstract

purposeCancer-related fatigue (CRF) is challenging to diagnose and manage due to a lack of consensus on its definition and assessment. The objective of this scoping review is to summarize how CRF has been defined and assessed in adult patients with cancer worldwide.

methodsFour databases (PubMed, Embase, CINAHL Plus, PsycNet) were searched to identify eligible original research articles published in English over a 10-year span (2010-2020); CRF was required to be a primary outcome and described as a dimensional construct. Each review phase was piloted: title and abstract screening, full-text screening, and data extraction. Then, two independent reviewers participated in each review phase, and discrepancies were resolved by a third party.

results2923 articles were screened, and 150 were included. Only 68% of articles provided a definition for CRF, of which 90% described CRF as a multidimensional construct, and 41% were identical to the National Comprehensive Cancer Network definition. Studies were primarily conducted in the United States (19%) and the majority employed longitudinal (67%), quantitative (93%), and observational (57%) study designs with sample sizes ≥ 100 people (57%). Participant age and race were often not reported (31% and 82%, respectively). The most common cancer diagnosis and treatment were breast cancer (79%) and chemotherapy (80%; n = 86), respectively. CRF measures were predominantly multidimensional (97%, n = 139), with the Multidimensional Fatigue Inventory (MFI-20) (26%) as the most common CRF measure and "Physical" (76%) as the most common CRF dimension.

conclusionThis review confirms the need for a universally agreed-upon definition and standardized assessment battery for CRF.

Indexed as

FatigueNeoplasmsHumansQuality of LifeCancer-related fatigueFatigue assessmentFatigue definitionFatigue dimensionScoping review

Identifiers

PMID38916815
PMCPMC11199267

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.