Evidence map›Paper›PMID 38916719›Full record

ArticleDermatology and therapy2024

Canadian Expert Consensus on the Use of Halobetasol Propionate/Tazarotene Lotion for Plaque Psoriasis.

Lyn Guenther, Irina Turchin, Ron Vender, Lorne E Albrecht, Catherine Maari, Howard Yanofsky, Vimal H Prajapati

Abstract read
In one paragraph

Article in Dermatology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lyn GuentherGuenther Research Inc., 835 Richmond St., London, ON, N6A 3H7, Canada. dgue@guenthermpc.com.ORCID http://orcid.org/0000-0001-9286-1534
Irina TurchinBrunswick Dermatology Centre, Fredericton, NB, Canada.ORCID http://orcid.org/0000-0001-8654-9050
Ron VenderDermatrials Research Inc, Hamilton, ON, Canada.ORCID http://orcid.org/0000-0002-2624-2724
Lorne E AlbrechtEnverus Medical Research, Surrey, BC, Canada.ORCID http://orcid.org/0000-0003-1718-884X
Catherine MaariInnovaderm Research, Montreal, QC, Canada.ORCID http://orcid.org/0000-0002-9719-0810
Howard YanofskyHoward Yanofsky Medical Services Inc., Montreal, QC, Canada.ORCID http://orcid.org/0000-0002-6473-4586
Vimal H PrajapatiProbity Medical Research, Waterloo, ON, Canada.ORCID http://orcid.org/0000-0002-8315-2522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAn expert panel of Canadian dermatologists was assembled to develop consensus statements regarding the current landscape of topical therapies for plaque psoriasis and the place in therapy of the recently approved fixed-dose combination halobetasol propionate (HP)/tazarotene (TAZ) lotion (HP/TAZ) in the treatment algorithm for plaque psoriasis.

methodA modified nominal group technique, which combined both independent and group input from the expert panel, was used to develop the consensus statements. The expert panel completed surveys to elicit their independent views on the current landscape of topical therapies for plaque psoriasis in Canada. The first expert panel session was held to discuss the existing body of literature and develop draft consensus statements about topical therapies and the place in therapy of HP/TAZ. Independent feedback on the draft consensus statements was solicited from expert panel members prior to another expert panel session where the amended consensus statements were further discussed, edited and, finally, voted on.

resultsThe expert panel reached consensus on 20 statements.

conclusionExpert panel members agreed, based on the existing body of literature, that there is a place in therapy for HP/TAZ to address several current unmet treatment needs of patients with plaque psoriasis. Studies have shown that HP/TAZ is an effective and safe first-line treatment for moderate-to-severe plaque psoriasis. Due to its cosmetically pleasing vehicle and once-daily administration, HP/TAZ may improve patient acceptance and treatment adherence.

Indexed as

ConsensusCorticosteroidHalobetasolPlaque psoriasisRetinoidTazaroteneTopical therapy

Identifiers

PMID38916719
PMCPMC11264667

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.