Observational studyQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024
Lower extremity physical function and quality of life in patients with stroke: a longitudinal cohort study.
Observational study in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Flexible exoskeleton-assisted training enhances lower limb motor function after stroke: a systematic review and meta-analysis.Journal of neurology · 2025Pooled it
- Health-Related Quality of Life in Survivors of Stroke Post Inpatient Rehabilitation Discharged to a Home Setting.Archives of rehabilitation research and clinical translation · 2025Article
- Alterations in Supine Position Mobility and Dynamics in Post-Stroke Individuals with Hemiparesis Compared to Neurologically Intact Controls: A Video-Based Observational Assessement.Journal of clinical medicine · 2025Article
- Association of kidney function and proteinuria with lower-extremity dysfunction in older Korean adults: a cross-sectional study.The Korean journal of internal medicine · 2025Article
- Evaluating core stability training-based combination therapies for lower extremity dysfunction post-stroke: a systematic review and network meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Effect of dry needling plus static stretching on plantar flexor spasticity, function, and quality of life in a patient with chronic stroke: a case report.Journal of medical case reports · 2025Article
- Mobility status, nutritional intervention and meal eaten are associated with discharge home: the nutritionDay study in China.Frontiers in nutrition · 2025Article
- Association between lower extremity physical function and physical activity after ischemic stroke: Longitudinal findings from the MOBITEC-Stroke project.SAGE open medicine · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLower extremity physical function (LEPF) is a key component for mobility and is impacted in stroke-related disability. A reduction in LEPF can have a significant impact on an individual's Quality of Life (QoL). The aim of this study is to characterise the relationship between LEPF and QoL.
methodsThe MOBITEC-Stroke Study is a longitudinal cohort-study including patients with their first occurrence of ischaemic stroke. Using a linear mixed-effects model, the relationship between LEPF (timed up-and-go performance (TUG); predictor) and QoL (Stroke Specific Quality of Life scale (SS-QoL); outcome) at 3 and 12 months post stroke was investigated and adjusted for sex, age, Instrumental Activities of Daily Living (IADL), fear of falling (Falls Efficacy Scale-International Version, FES-I), and stroke severity (National Institute of Stroke Severity scale, NIHSS), accounting for the repeated measurements.
resultsData of 51 patients (65 % males, 35% females) were analysed. The mean age was 71.1 (SD 10.4) years, median NIHSS score was 2.0. SS-QoL was 201.5 (SD 20.5) at 3 months and 204.2 (SD 17.4) at 12 months; the mean change was 2.7 (95% CI -2.4 to 7.7), p= 0.293. A positive association was found between baseline TUG performance (estimate log score -13.923; 95% CI -27.495 to -0.351; p=0.048) and change in SS-QoL score in multivariate regression analysis.
conclusionHigher LEPF (i.e better TUG performance) at baseline, was associated with an improvement in QoL from 3- to 12-months post stroke. These results highlight the critical role of physical function, particularly baseline LEPF, in influencing the QoL of stroke survivors.
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