Evidence map›Paper›PMID 38916624›Full record

SynthesisWorld journal of urology2024

Retzius sparing robot-assisted radical prostatectomy: optimizing functional results.

Francesco Chierigo, Alberto Caviglia, Valerio Cellini, Stefano Tappero, Michael Aigner, Erika Palagonia, Alberto Olivero, Silvia Secco, Aldo Massimo Bocciardi, Paolo Dell'Oglio and 1 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco ChierigoDepartment of Urology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID http://orcid.org/0000-0001-7357-0758
Alberto CavigliaDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Valerio CelliniDepartment of General Surgery and Surgical Specialties, Azienda Ospedaliera "S. Maria" of Terni, Terni, Italy.
Stefano TapperoDepartment of Urology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Michael AignerDepartment of Urology, Südtiroler Sanitätsbetrieb, Azienda Sanitaria dell'Alto Adige, Krankenhaus Brixen, Ospedale di Bressanone, Brixen, Italy.
Erika PalagoniaDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Alberto OliveroDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Silvia SeccoDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Aldo Massimo BocciardiDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Paolo Dell'OglioDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Antonio GalfanoDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy. antoniogalfano@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to critically evaluate the existing body of evidence regarding the efficacy of Retzius-sparing radical prostatectomy (RS-RARP) in achieving improved functional outcomes. Moreover, we explored possible strategies to further optimize functional outcomes.

methodsFollowing PRISMA guidelines, a systematic review (PROSPERO ID CRD42024539915) was performed on 9th September 2023 on PubMed, Scopus, and Web of Science. Only original articles in the English language reporting functional outcomes after RS-RARP were included.

resultsOverall, the search string yielded 99 results on PubMed, 122 on Scopus, and 120 on Web Of Science. After duplicate exclusion, initial screening and eligibility evaluation, a total of 47 studies were included in the qualitative analysis, corresponding to a cohort of 13.196 patients. All studies reported continence recovery. RS-RARP appeared to achieve better and faster continence recovery compared to S-RARP. However, it should be noted that continence definition was heterogeneous and not based on validated condition-specific questionnaires. Seven (15%) studies provided for any sort of rehabilitation for urinary incontinence after RS-RARP. 22 studies analyzed potency recovery rates, showing no difference between RS-RARP and S-RARP. The evaluation of this outcome poses a great challenge due to the lack of standardized assessment tools and reporting methods. Only two studies reported on the consistent use of post-operative PDE5i as penile rehabilitation.

conclusionsThe current review highlights the satisfactory functional results of Retzius-sparing robot assisted radical prostatectomy, which holds true irrespective of disease stage and prostate volume, with promising results even in patients previously treated for BPH or in the salvage setting. How can we optimize those results? The answer does not probably lie in further refinement of the surgical technique, but in giving greater attention to patient counselling and rehabilitation strategies in order to minimize regret and maximize satisfaction.

Indexed as

Organ Sparing TreatmentsProstatectomyProstatic NeoplasmsRecovery of FunctionRobotic Surgical ProceduresHumansMaleTreatment OutcomeUrinary IncontinenceErectile functionFunctional outcomesProstate cancerRadical prostatectomyRetzius-sparingSystematic reviewUrinary continence

Identifiers

PMID38916624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.