Evidence map›Paper›PMID 38916407›Full record

ArticleEmerging microbes & infections2024

The nuclear localization signal of monkeypox virus protein P2 orthologue is critical for inhibition of IRF3-mediated innate immunity.

Pengtao Jiao, Jianing Ma, Yuna Zhao, Xiaoxiao Jia, Haoran Zhang, Wenhui Fan, Xiaojuan Jia, Xiaoyuan Bai, Yiqi Zhao, Yongxu Lu and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Monkeypox virus protein OPG188 antagonizes cGAS-STING antiviral signaling pathway to mediate immune evasion.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Pengtao JiaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Jianing MaCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Yuna ZhaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Xiaoxiao JiaCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Haoran ZhangCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Wenhui FanCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Xiaojuan JiaCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Xiaoyuan BaiCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Yiqi ZhaoSir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Yongxu LuSir William Dunn School of Pathology, University of Oxford, Oxford, UK.
He ZhangInstitute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen, People's Republic of China.
Jiayin GuoShanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, People's Republic of China.
Gang PangShanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, People's Republic of China.
Ke ZhangShanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, People's Republic of China.
Min FangSchool of Life Sciences, Henan University, Kaifeng, People's Republic of China.
Minghua LiKunming National High-level Biosafety Research Center for Non-Human Primates, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, People's Republic of China.
Wenjun LiuCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Geoffrey L SmithSir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Lei SunCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.ORCID 0000-0003-0141-2093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

Immunity, InnateInterferon Regulatory Factor-3Monkeypox virusNuclear Localization SignalsViral Proteinsalpha KaryopherinsAnimalsCell NucleusHEK293 CellsHumansImmune EvasionInterferonsMiceMice, Inbred C57BLPoxviridae Infectionsalpha KaryopherinsInterferon Regulatory Factor-3InterferonsNuclear Localization SignalsViral Proteinsimmune evasioninnate immunityIRF3monkeypox virusOrthopoxvirus

Identifiers

PMID38916407
PMCPMC11229740

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.