Evidence map›Paper›PMID 38916244›Full record

ArticleJournal of the American Chemical Society2024

Automated Synthesis of Algal Fucoidan Oligosaccharides.

Conor J Crawford, Mikkel Schultz-Johansen, Phuong Luong, Silvia Vidal-Melgosa, Jan-Hendrik Hehemann, Peter H Seeberger

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
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  3. Article
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  6. Review
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  9. Article
  10. Article
  11. Journal of the American Society for Mass Spectrometry · 2025
    Article
  12. Activity-Based Tracking of Glycan Turnover in Microbiomes.Journal of the American Chemical Society · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Expediting Glycospace Exploration: Therapeutic Glycans via Automated Synthesis.Angewandte Chemie (International ed. in English) · 2025
    Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Conor J CrawfordMax Planck Institute for Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.ORCID 0000-0002-1314-1019
Mikkel Schultz-JohansenMax Planck Institute for Marine Microbiology, Celsiusstraße 1, 28359 Bremen, Germany.ORCID 0000-0001-7868-1078
Phuong LuongMax Planck Institute for Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.
Silvia Vidal-MelgosaMax Planck Institute for Marine Microbiology, Celsiusstraße 1, 28359 Bremen, Germany.ORCID 0000-0002-9408-2849
Jan-Hendrik HehemannMax Planck Institute for Marine Microbiology, Celsiusstraße 1, 28359 Bremen, Germany.
Peter H SeebergerMax Planck Institute for Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.ORCID 0000-0003-3394-8466

Funding

European Research Council 101044738
6 · The paper itself

Abstract

Fucoidan, a sulfated polysaccharide found in algae, plays a central role in marine carbon sequestration and exhibits a wide array of bioactivities. However, the molecular diversity and structural complexity of fucoidan hinder precise structure-function studies. To address this, we present an automated method for generating well-defined linear and branched α-fucan oligosaccharides. Our syntheses include oligosaccharides with up to 20

Indexed as

OligosaccharidesPolysaccharidesAntibodies, MonoclonalAutomationDiatomsGlycoside HydrolasesPhaeophyceaeAntibodies, MonoclonalfucoidanGlycoside HydrolasesOligosaccharidesPolysaccharides

Identifiers

PMID38916244
PMCPMC11240576

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.