Evidence map›Paper›PMID 38916220›Full record

ArticleEnvironmental science & technology2024

Combining Nontargeted Analysis with Computer-Based Hazard Comparison Approaches to Support Prioritization of Unregulated Organic Contaminants in Biosolids.

Matthew N Newmeyer, Qinfan Lyu, Jon R Sobus, Antony J Williams, Keeve E Nachman, Carsten Prasse

Abstract read
In one paragraph

Article in Environmental science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew N NewmeyerDepartment of Environmental Health and Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.ORCID 0000-0002-0653-1553
Qinfan LyuDepartment of Environmental Health and Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.
Jon R SobusCenter for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27709, United States.
Antony J WilliamsCenter for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27709, United States.ORCID 0000-0002-2668-4821
Keeve E NachmanDepartment of Environmental Health and Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.
Carsten PrasseDepartment of Environmental Health and Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.ORCID 0000-0002-1470-141X

Funding

EPA R840247Intramural EPA EPA999999NIOSH CDC HHS T42 OH008428
6 · The paper itself

Abstract

Biosolids are a byproduct of wastewater treatment that can be beneficially applied to agricultural land as a fertilizer. While U.S. regulations limit metals and pathogens in biosolids intended for land applications, no organic contaminants are currently regulated. Novel techniques can aid in detection, evaluation, and prioritization of biosolid-associated organic contaminants (BOCs). For example, nontargeted analysis (NTA) can detect a broad range of chemicals, producing data sets representing thousands of measured analytes that can be combined with computational toxicological tools to support human and ecological hazard assessment and prioritization. We combined NTA with a computer-based tool from the U.S. EPA, the Cheminformatics Hazard Comparison Module (HCM), to identify and prioritize BOCs present in U.S. and Canadian biosolids (

Indexed as

WastewaterEnvironmental MonitoringHumansOrganic ChemicalsOrganic ChemicalsWastewaterchemical spaceenvironmental monitoringhigh-resolution mass spectrometrysludgewastewater

Identifiers

PMID38916220
PMCPMC11381038

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.