Evidence map›Paper›PMID 38916180›Full record

ArticleActa dermato-venereologica2024

Treatment of Brachioradial Pruritus: A Tertiary Center Retrospective Analysis.

Kayla D Mashoudy, Luis F Andrade, Nicole Khalil, Ellie H Zhang, Jaxon D Wagner, Bharat Malhotra, Gil Yosipovitch

Abstract readComparative Study
In one paragraph

Article in Acta dermato-venereologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kayla D MashoudyUniversity of Miami Miller School of Medicine, Miami, USA. kmashoudy@med.miami.edu.
Luis F AndradeUniversity of Miami Miller School of Medicine, Miami, USA.
Nicole KhalilUniversity of Miami Miller School of Medicine, Miami, USA.
Ellie H ZhangUniversity of Miami Miller School of Medicine, Miami, USA.
Jaxon D WagnerUniversity of Miami Miller School of Medicine, Miami, USA.
Bharat MalhotraUniversity of Miami Miller School of Medicine, Miami, USA.
Gil YosipovitchDr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective study investigates the efficacy of 2 treatment regimens, pregabalin alone versus pregabalin combined with ketamine, amitriptyline, and lidocaine cream, in reducing itch in patients with brachioradial pruritus at a tertiary care center. Electronic medical records of 64 brachioradial pruritus patients seen at the University of Miami Itch Center were analyzed. A significant reduction in itch scores was seen with both treatments, with no significant difference between the groups. A small number of patients experienced adverse effects, including drowsiness and weight gain with pregabalin and skin irritation with ketamine, amitriptyline, and lidocaine cream. Ultimately, our findings underscore the potential of utilizing combined therapy for difficult-to-treat brachioradial pruritus cases and implementing individualized approaches for managing neuropathic pruritus. Further controlled clinical trials are needed to establish optimal treatment protocols.

Indexed as

AmitriptylineDrug Therapy, CombinationKetamineLidocainePregabalinPruritusTertiary Care CentersAdministration, CutaneousAdultAgedAntipruriticsElectronic Health RecordsFemaleFloridaHumansMaleAmitriptylineAntipruriticsKetamineLidocainePregabalin

Identifiers

PMID38916180
PMCPMC11218673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.