Evidence map›Paper›PMID 38916002›Full record

ArticleCureus2024

Spindle Cell Lipoma and Pleomorphic Lipoma in the Head and Neck: A Comprehensive Study of Six Cases With Review of Literature.

Subhash Yadav, Katha Rabade, Swapnil Rane, Asawari Patil, Neha Mittal, Sumankumar Ankathi, Sumeet Gujral, Bharat Rekhi, Munita Bal

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Subhash YadavDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Katha RabadeDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Swapnil RaneDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Asawari PatilDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Neha MittalDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Sumankumar AnkathiDepartment of Radiodiagnosis, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Sumeet GujralDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Bharat RekhiDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.
Munita BalDepartment of Surgical Pathology, Tata Memorial Hospital & Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) A Constituent Institution (CI) of Homi Bhabha National Institute, Mumbai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpindle cell lipomas (SL) and pleomorphic lipomas (PL) are rare variants of lipomas, occurring predominantly in the head and neck region. Laryngeal SL/PL is very uncommon and causes obstructive symptoms needing immediate intervention. These tumors are often challenging in radiology due to the admixture of elements and the presence of adipose tissue may help in diagnosis. From a surgeon's perspective, understanding the nuances of SL/PL is paramount. Histology is the gold standard for diagnosis; however, it often causes diagnostic challenges in biopsy.  Method: A retrospective review of the clinical and pathologic features of archival cases of SL/PL was performed.

resultsA total of six cases of head and neck region SL/PL were identified. The age of patients ranged from 21 to 58 years and the male-to-female ratio was 5:1. The tumors were distributed in the nape of the neck (n=3), laryngeal region (n=2), and orbit (n=1). Histology in all the cases showed a low-grade neoplasm composed of a variable amount of spindle cells and adipose tissue. The stroma was myxoid in most cases. CD34 was diffusely positive in all the cases.

conclusionSLs are a rare and uncommon variant of lipoma with a predilection in the head and neck region. They are low-grade neoplasms with a propensity to recur after years. Having knowledge of this tumor can improve surgical outcomes and better patient care.

Indexed as

cd34head and necklarynxlipomamolecular profilespindle cell

Identifiers

PMID38916002
PMCPMC11194465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.