Evidence map›Paper›PMID 38915971›Full record

ArticleCureus2024

Troponinemia in Patients With Diabetic Ketoacidosis Without Acute Coronary Syndrome.

Indira Poojary, Usbah Khalid, Tumpa Patra, Junu Giri, Ammar Al Heyasat, Sayeda Basith, Saketh Palasamudram Shekar, Anand Balachandran, Akram Haggag

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Indira PoojaryInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Usbah KhalidInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Tumpa PatraInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Junu GiriInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Ammar Al HeyasatInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Sayeda BasithFamily Medicine, Crestwood Medical Center, Huntsville, USA.
Saketh Palasamudram ShekarInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Anand BalachandranInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Akram HaggagInternal Medicine, Crestwood Medical Center, Huntsville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic myocardial injury in a diabetes mellitus (DM) patient can be a trigger or a complication of diabetic ketoacidosis (DKA). This case series examines the phenomenon of elevated troponin levels in patients with DKA in the absence of obstructive coronary artery disease. Two out of three cases showed ST-segment elevation on electrocardiogram (EKG). Despite the absence of obstructive coronary artery disease on coronary angiography, all cases exhibited troponinemia (>79 ng/dl). These elevated troponin levels and EKG changes may pose diagnostic challenges for clinicians. Alternatively, troponinemia could be due to myocardial injury caused by acidotic stress and free fatty acid utilization along with increased myocardial oxygen demand and not obstructive coronary artery pathology in every case. However, a better understanding of the complex interplay between DKA and myocardial injury needs further research.

Indexed as

acute coronary syndrome (acs)cardiac risk factors and preventioncardiac troponindiabetes mellitusdiabetic ketoacidosis

Identifiers

PMID38915971
PMCPMC11195327

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.