ReviewReproductive medicine and biology
Sperm morphology: Evaluating its clinical relevance in contemporary fertility practice.
Review in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- The Influence of Sexually Transmitted Bacteria and Human Papillomavirus on Sperm Parameters: Data from a Preliminary Study.Medicina (Kaunas, Lithuania) · 2026Article
- A Comparative Review of Fertility and Semen Assessment Techniques in Farm Animals.Animals : an open access journal from MDPI · 2026Review
- Deep learning-enabled morphology analysis of bovine sperm for label-free imaging flow cytometry.Frontiers in veterinary science · 2026Article
- A Novel Homozygous Mutation inHuman mutation · 2026Article
- Effects of fertilization media on in vitro embryonic development in red-rumped agouti () using a heterologous system with guinea pig oocytes.JBRA assisted reproduction · 2026Article
- Predictors of elevated sperm DNA fragmentation: a morphology-based approach to semen analysis.Basic and clinical andrology · 2025Article
- Oxidative stress and its correlation with sperm parameters in different semen quality groups.Clinical and experimental reproductive medicine · 2025Article
- Design and Implementation of a Deep Learning System to Analyze Bovine Sperm Morphology.Veterinary sciences · 2025Article
- Effects of Phytocannabinoids on Reproductive System and Prenatal Development: Mechanisms and Clinical Implications.Journal of clinical medicine · 2025Review
- Varicocele grade does not correlate with the severity of sperm DNA fragmentation levels nor with the amount of improvement in DNA fragmentation following varicocele repair.Translational andrology and urology · 2025Article
- Deep Learning Models for Multi-Part Morphological Segmentation and Evaluation of Live Unstained Human Sperm.Sensors (Basel, Switzerland) · 2025Article
- Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece.Frontiers in cell and developmental biology · 2025Article
- Article
- Sperm morphology: Evaluating its clinical relevance in contemporary fertility practice.Reproductive medicine and biologyReview
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The World Health Organization (WHO) recommends reporting sperm morphology in a standard semen analysis. However, the clinical utility and prognostic value of morphology is often debated. Methods: We reviewed and summarized studies that assessed both the benefits and limitations of sperm morphology in the context of natural fertility, assisted reproductive technologies, and recurrent pregnancy loss. We additionally describe possible environmental and anatomical etiologies of teratozoospermia. Results: Sperm morphology evaluation has continuously evolved since the release of the first WHO manual in 1980. Initially, several large studies reported significant inverse associations between fertility outcomes and teratozoospermia. Most recent studies, however, fail to show an association between sperm morphology and natural or assisted fertility outcomes. Conclusion: Sperm morphology analysis may have limited diagnostic and prognostic value. Providers should be aware of these limitations when counseling or managing infertile patients.
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