Evidence map›Paper›PMID 38915596›Full record

ArticlebioRxiv : the preprint server for biology2024

Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances.

Jian Qiu, Margaritis Voliotis, Martha A Bosch, Xiao Feng Li, Larry S Zweifel, Krasimira Tsaneva-Atanasova, Kevin T O'Byrne, Oline K Rønnekleiv, Martin J Kelly

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jian QiuDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science U., Portland, OR 97239, USA.ORCID 0000-0002-4988-8587
Margaritis VoliotisDepartment of Mathematics and Statistics, University of Exeter, Stocker Rd, Exeter, EX4 4PY, UK.ORCID 0000-0001-6488-7198
Martha A BoschDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science U., Portland, OR 97239, USA.
Xiao Feng LiDepartment of Women and Children's Health, School of Life Course and Population Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.
Larry S ZweifelDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-3465-5331
Krasimira Tsaneva-AtanasovaDepartment of Mathematics and Statistics, University of Exeter, Stocker Rd, Exeter, EX4 4PY, UK.ORCID 0000-0002-6294-7051
Kevin T O'ByrneDepartment of Women and Children's Health, School of Life Course and Population Sciences, King's College London, Guy's Campus, London SE1 1UL, UK.ORCID 0000-0002-2548-4182
Oline K RønnekleivDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science U., Portland, OR 97239, USA.ORCID 0000-0003-1841-4386
Martin J KellyDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science U., Portland, OR 97239, USA.ORCID 0000-0002-8633-2510

Funding

University of Washington Center of Excellence in Opioid Addiction ResearchP30DA048736 · NIDA · UNIVERSITY OF WASHINGTON · PI Charles Chavkin · 2019 to 2026
$13.0M
Sex Differences in the Control of FeedingR01DK068098 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI KELLY, MARTIN JEFFREY, RØNNEKLEIV, OLINE KARIN · 2005 to 2024
$7.1M
NIDA NIH HHS P30 DA048736NIDDK NIH HHS R01 DK068098
6 · The paper itself

Abstract

Hypothalamic kisspeptin (Kiss1) neurons are vital for pubertal development and reproduction. Arcuate nucleus Kiss1 (Kiss1

Indexed as

17β-estradiolArcuate nucleusBurst firingIon channelsKisspeptinMathematical modelingSynchronous firing

Identifiers

PMID38915596
PMCPMC11195100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.