Evidence map›Paper›PMID 38915376›Full record

ReviewCardiac failure review2024

Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review.

Moza A Alzaabi, Amin Abdelsalam, Majid Alhammadi, Hasan Bani Hani, Ali Almheiri, Nadya Al Matrooshi, Khaled Al Zaman

Abstract readReview
In one paragraph

Review in Cardiac failure review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Diagnostic Tests for Stage B Heart Failure.Current cardiology reports · 2026
    Review
  5. Article
  6. Article
  7. Article
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  9. BUN-albumin ratio as a prognostic marker in decompensated heart failure with reduced ejection fraction.American heart journal plus : cardiology research and practice · 2026
    Article
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  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Moza A AlzaabiCardiothoracic Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic Abu Dhabi Abu Dhabi, United Arab Emirates.
Amin AbdelsalamDepartment of Cardiology, Al Qassemi Hospital Sharjah, United Arab Emirates.
Majid AlhammadiCollege of Medicine, University of Sharjah Sharjah, United Arab Emirates.
Hasan Bani HaniCollege of Medicine, University of Sharjah Sharjah, United Arab Emirates.
Ali AlmheiriCollege of Medicine, University of Sharjah Sharjah, United Arab Emirates.
Nadya Al MatrooshiCardiothoracic Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic Abu Dhabi Abu Dhabi, United Arab Emirates.
Khaled Al ZamanCardiothoracic Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic Abu Dhabi Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a high prevalence of heart failure (HF) worldwide, which has significant consequences for healthcare costs, patient death and quality of life. Therefore, there has been much focus on finding and using biomarkers for early diagnosis, prognostication and therapy of HF. This overview of the research presents a thorough examination of the current state of HF biomarkers and their many uses. Their function in diagnosing HF, gauging its severity and monitoring its response to therapy are all discussed. Particularly promising in HF diagnosis and risk stratification are the cardiac-specific biomarkers, B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide. Markers of oxidative stress, extracellular matrix, renal function, inflammation and cardiac peptides have shown promise in evaluating HF severity and prognosis. MicroRNAs and insulin-like growth factor are two emerging biomarkers that have shown potential in helping with HF diagnosis and prognosis.

Indexed as

Biomarkerbiomarkersheart failureprognosis

Identifiers

PMID38915376
PMCPMC11194781

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.