Evidence map›Paper›PMID 38915177›Full record

ArticleJMIR medical informatics2024

Implementing a Biomedical Data Warehouse From Blueprint to Bedside in a Regional French University Hospital Setting: Unveiling Processes, Overcoming Challenges, and Extracting Clinical Insight.

Matilde Karakachoff, Thomas Goronflot, Sandrine Coudol, Delphine Toublant, Adrien Bazoge, Pacôme Constant Dit Beaufils, Emilie Varey, Christophe Leux, Nicolas Mauduit, Matthieu Wargny and 1 more

Abstract read
In one paragraph

Article in JMIR medical informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matilde KarakachoffCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0003-4318-9141
Thomas GoronflotCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0002-1019-9821
Sandrine CoudolCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0009-0004-5095-1813
Delphine ToublantCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0002-4464-0996
Adrien BazogeCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0002-9723-9688
Pacôme Constant Dit BeaufilsCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0002-0466-2816
Emilie VareyCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0002-3013-2472
Christophe LeuxService d'information médicale, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0009-0001-6398-5578
Nicolas MauduitService d'information médicale, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0009-0005-8433-2815
Matthieu WargnyCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0001-6027-9486
Pierre-Antoine GourraudCentre d'Investigation Clinique 1413, INSERM, Clinique des données, Pôle Hospitalo-Universitaire 11: Santé Publique, Centre Hospitalier Universitaire Nantes, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0003-1131-9554

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Biomedical data warehouses (BDWs) have become an essential tool to facilitate the reuse of health data for both research and decisional applications. Beyond technical issues, the implementation of BDWs requires strong institutional data governance and operational knowledge of the European and national legal framework for the management of research data access and use. Objective: In this paper, we describe the compound process of implementation and the contents of a regional university hospital BDW. Methods: We present the actions and challenges regarding organizational changes, technical architecture, and shared governance that took place to develop the Nantes BDW. We describe the process to access clinical contents, give details about patient data protection, and use examples to illustrate merging clinical insights. Unlabelled: More than 68 million textual documents and 543 million pieces of coded information concerning approximately 1.5 million patients admitted to CHUN between 2002 and 2022 can be queried and transformed to be made available to investigators. Since its creation in 2018, 269 projects have benefited from the Nantes BDW. Access to data is organized according to data use and regulatory requirements. Conclusions: Data use is entirely determined by the scientific question posed. It is the vector of legitimacy of data access for secondary use. Enabling access to a BDW is a game changer for research and all operational situations in need of data. Finally, data governance must prevail over technical issues in institution data strategy vis-à-vis care professionals and patients alike.

Indexed as

biomedical data warehouseclinical data repositoryclinical routine datadata reusedata warehouseelectronic health recordsimplementation reportreal-world datasecondary use

Identifiers

PMID38915177
PMCPMC11217163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.