ArticleBMC public health2024
Malaria in under-five children: prevalence and multi-factor analysis of high-risk African countries.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Burden of malaria infection among most vulnerable populations in Ethiopia: an umbrella review of systematic reviews and meta-analyses.BMC infectious diseases · 2025Pooled it
- Determinants of malaria prevalence among children under 5 years of age in 17 sub-Saharan African countries: insights from Malaria Indicator Surveys.Global health action · 2026Article
- Prevalence, determinants, and wealth-related inequalities in malaria among under five children in Uganda: evidence from the malaria indicator survey.Infectious diseases of poverty · 2026Article
- Clinical malaria recurrence and associated factors in infancy following IPTp-DP versus IPTp-SP in Busia, Uganda; a secondary analysis using the Conditional Frailty model.Malaria journal · 2026Article
- Implementing seasonal malaria chemoprevention in conflict-affected settings: experiences from Northern Bahr el Ghazal, South Sudan.Malaria journal · 2026Article
- One health perspectives on the epidemiological features and changing incidence of natural focus and vector-borne infectious diseases in China: An observational trend study.One health (Amsterdam, Netherlands) · 2026Article
- Burden of diarrheal diseases among children under five in East Africa, 2000-2023: insights from the global burden of disease 2023 study.BMC infectious diseases · 2026Article
- Spatial epidemiology of malaria by bed net utilization in 19 sub-Saharan African countries: a DHS-based study (2013-2023).Malaria journal · 2026Article
- Anti-GPI scFv as a Promising Tool for Intervention Against Cerebral Malaria in Mice.International journal of molecular sciences · 2026Article
- α-Thalassemia has no association with asymptomatic Plasmodium falciparum carriage in three ecological zones of Ghana.Scientific reports · 2026Article
- Sociodemographic and healthcare determinants of malaria infection among children under five in Burkina Faso: analysis of the 2021 Demographic and Health Survey data.Malaria journal · 2026Article
- Prevalence and factors associated with malaria among children aged 6-59 months in the Democratic Republic of the Congo: a nationwide cross-sectional survey.Malaria journal · 2026Article
- Prevalence and Type Distribution of Malaria Among Children in Ethiopia: A Systematic Review and Meta-Analysis.Journal of parasitology research · 2026Review
- Article
- Sociodemographic and socioeconomic predictors of asymptomatic malaria among children and adolescents in rural Guinea: a longitudinal study.Frontiers in public health · 2026Article
- Knowledge, attitudes and factors associated with the awareness of caregivers of under-five children regarding the malaria vaccine in the Tiko Health District, Cameroon: A community-based cross-sectional study.PLOS global public health · 2026Article
- Burden of anaemia in displaced women and children in refugee settings worldwide, update for 2017-2024: a cross-sectional study.BMJ open · 2025Article
- Associations between undernutrition and malaria infection: a case-control study from Rwanda.Malaria journal · 2025Article
- Blood donors as a sentinel population for real-time malaria surveillance using the Sysmex XN-31: a one-year review from the National Blood Transfusion Centre in Burkina Faso.Malaria journal · 2025Article
- Prevalence and determinants of malaria among children aged 6-59 months in Tanzania: a nationwide cross-sectional study.Malaria journal · 2025Article
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7 authors.
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Abstract
backgroundMalaria remains a significant public health challenge in Sub-Saharan Africa (SSA), particularly affecting under-five (UN5) children. Despite global efforts to control the disease, its prevalence in high-risk African countries continues to be alarming, with records of substantial morbidity and mortality rates. Understanding the association of multiple childhood, maternal, and household factors with malaria prevalence, especially among vulnerable young populations, is crucial for effective intervention strategies.
objectiveThis study examines the prevalence of malaria among UN5 children in selected high-risk SSA countries and analyzes its association with various childhood, maternal, and household factors.
methodsData from the Malaria Indicator Surveys (MIS) spanning from 2010 to 2023 were analyzed. A weighted sample of 35,624 UN5 children from seven countries in sub-Saharan Africa (SSA) known for high malaria prevalence was considered in the analyses. Descriptive statistics and modified Poisson regression analysis were used to assess the association of multiple factors with malaria prevalence. Stata version 15 software was used in analyzing the data and statistical significance was set at a 5% significance level.
resultsThe overall pooled prevalence of malaria among the studied population was 26.2%, with substantial country-specific variations observed. In terms of child factors, a child's age was significantly associated with malaria prevalence (APR = 1.010, 95% CI: 1.007-1.012). Children of mothers with higher education levels (APR for higher education = 0.586, 95% CI: 0.425-0.806) and Fansidar uptake during pregnancy (APR = 0.731, 95% CI: 0.666-0.802) were associated with lower malaria risk. Children from middle-wealth (APR = 0.783, 95% CI: 0.706-0.869) and rich (APR = 0.499, 95% CI: 0.426-0.584) households had considerably lower malaria prevalence compared to those from poor households. Additionally, rural residency was associated with a higher risk of malaria compared to urban residency (APR = 1.545, 95% CI: 1.255-1.903).
conclusionThe study highlights a notable malaria prevalence among under-five (UN5) children in high-risk SSA countries, influenced significantly by factors such as maternal education, Fansidar uptake during pregnancy, socioeconomic status, and residency. These findings underscore the importance of targeted malaria prevention strategies that address these key determinants to effectively reduce the malaria burden in this vulnerable population.
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