Evidence map›Paper›PMID 38914895›Full record

ArticleBrain structure & function2024

Clinical and structural disconnectome evaluation in a case of optic aphasia.

Laura Veronelli, Rolando Bonandrini, Alessandra Caporali, Daniele Licciardo, Massimo Corbo, Claudio Luzzatti

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In one paragraph

Article in Brain structure & function, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Laura VeronelliDepartment of Psychology, University of Milano-Bicocca and Milan Center for Neuroscience, Milan, Italy. laura.veronelli@unimib.it.ORCID http://orcid.org/0000-0001-7839-3324
Rolando BonandriniDepartment of Psychology, University of Milano-Bicocca and Milan Center for Neuroscience, Milan, Italy.
Alessandra CaporaliDepartment of Neurorehabilitation Sciences, Casa di Cura IGEA, Milan, Italy.
Daniele LicciardoDepartment of Psychology, University of Milano-Bicocca and Milan Center for Neuroscience, Milan, Italy.
Massimo CorboDepartment of Neurorehabilitation Sciences, Casa di Cura IGEA, Milan, Italy.
Claudio LuzzattiDepartment of Psychology, University of Milano-Bicocca and Milan Center for Neuroscience, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optic Aphasia (OA) and Associative Visual Agnosia (AVA) are neuropsychological disorders characterized by impaired naming on visual presentation. From a cognitive point of view, while stimulus identification is largely unimpaired in OA (where access to semantic knowledge is still possible), in AVA it is not. OA has been linked with right hemianopia and disconnection of the occipital right-hemisphere (RH) visual processing from the left hemisphere (LH) language areas.In this paper, we describe the case of AA, an 81-year-old housewife suffering from a deficit in naming visually presented stimuli after left occipital lesion and damage to the interhemispheric splenial pathway. AA has been tested through a set of tasks assessing different levels of visual object processing. We discuss behavioral performance as well as the pattern of lesion and disconnection in relation to a neurocognitive model adapted from Luzzatti and colleagues (1998). Despite the complexity of the neuropsychological picture, behavioral data suggest that semantic access from visual input is possible, while a lesion-based structural disconnectome investigation demonstrated the splenial involvement.Altogether, neuropsychological and neuroanatomical findings support the assumption of visuo-verbal callosal disconnection compatible with a diagnosis of OA.

Indexed as

Neuropsychological TestsAged, 80 and overAgnosiaAphasiaCorpus CallosumFemaleHumansMagnetic Resonance ImagingOccipital LobeVisual PerceptionAssociative visual agnosiaDisconnectomeOccipital lobeOptic aphasiaSemanticsSplenial disconnection

Identifiers

PMID38914895
PMCPMC11374911

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.