Evidence map›Paper›PMID 38914606›Full record

ArticleScientific reports2024

Comparison of visual outcomes and optical aberrations after SMILE with intraoperative Kappa angle adjustments between small and large Kappa angles.

Xiaojuan Lai, Xi Liu, Tao Zeng, Yi Huang, Xin Yang

2 registry-linked trialsAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07512102 narecruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Low- Versus High-Level Angle Kappa Compensation Strategies in SMILE Using the VisuMax 800: A Randomized Clinical Trial

TypeinterventionalSponsorZhongshan Ophthalmic Center, Sun Yat-sen UniversityRan2026 to 2027Enrolled100ConditionsMyopia, Refractive AmetropiaArmsApply high compensation to the Kappa angle., Apply low compensation to the Kappa angle.
NCT07512115 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Centration Compensation on Visual Quality in VisuMax 800 SMILE for Small Kappa Angles: A Randomized Trial

TypeinterventionalSponsorZhongshan Ophthalmic Center, Sun Yat-sen UniversityRan2026 to 2027Enrolled224ConditionsMyopia, Refractive AmetropiaArmsApply compensation to the Kappa angle., Apply no compensation to the Kappa angle
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaojuan LaiDepartment of Ophthalmology, The Second People's Hospital of Yibin, Yi'bin, 644000, China.
Xi LiuDepartment of Ophthalmology, The Second People's Hospital of Yibin, Yi'bin, 644000, China. xiliu.yibinhospital@outlook.com.
Tao ZengDepartment of Ophthalmology, The Second People's Hospital of Yibin, Yi'bin, 644000, China.
Yi HuangDepartment of Ophthalmology, The Second People's Hospital of Yibin, Yi'bin, 644000, China.
Xin YangThe University of Alabama, Tuscaloosa, AL, 35487, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compares postoperative visual outcomes and optical aberrations after Small Incision Lenticule Extraction (SMILE) in patients with both small (S-Kappa: Kappa angle < 0.2 mm) and large Kappa (L-Kappa: Kappa angle ≥ 0.2 mm) angles. The evaluated aberrations include total higher-order aberrations (HOAs), horizontal coma (HC), vertical coma (VC), and spherical aberrations (SA), with procedures incorporating intraoperative Kappa angle adjustments. We retrospectively analyzed patient records undergoing SMILE utilizing linear mixed models (LMM). We assessed adjusted mean uncorrected distance visual acuity (UDVA), Strehl ratio (SR), total HOAs, VC, and SA at pupils of 3 mm and 6 mm for both S-Kappa and L-Kappa. The disparities between S-Kappa and L-Kappa were evaluated by LMM's adjusted mean differences. The differences in optical metrics were also assessed in eyes grouped by myopia levels: low, moderate, and high. A sensitivity analysis was conducted on a threshold of Kappa angle at 0.3 mm. Eight-five patients (169 eyes) were analyzed, and no significant pre-operative difference was found in UDVA (p = .222) or spherical equivalent (p = .433). Post-operative differences were found in SR at 3 mm pupil size (-0.06, p = .022), total HOA 3 mm (0.15, p = .022), HC 3 mm (0.04, p = .042), VC 3 mm and 6 mm (-0.08, p = .041; 0.04, p = .041). The stratified analysis for high myopia revealed significant differences in UDVA (-0.04, p = .037), HC 3 mm (0.07, p = .03), VC 6 mm (-0.21, p = .001), and SA 3 mm and 6 mm (0.07, p = .037; -0.09, p = .037). Sensitivity analysis showed no significant difference using a 0.3 mm Kappa threshold. While some optical aberrations exhibited statistical differences between S-Kappa and L-Kappa, their clinical significance is limited. Thus, a large Kappa angle might not substantially influence post-operative optical aberrations when intraoperative Kappa angle adjustments are implemented.

Indexed as

MyopiaVisual AcuityAdultCorneal Surgery, LaserCorneal Wavefront AberrationFemaleHumansMaleRefraction, OcularRetrospective StudiesTreatment OutcomeYoung Adult

Identifiers

PMID38914606
PMCPMC11196622

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.