ArticleAJNR. American journal of neuroradiology2024
Prevalence of Rathke Cleft and Other Incidental Pituitary Gland Findings on Contrast-Enhanced 3D Fat-Saturated T1 MPRAGE at 7T MRI.
Article in AJNR. American journal of neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Spontaneous regression of Rathke's cleft cysts: MRI predictors and temporal dynamics.Neuroradiology · 2026Article
- Case report of transsphenoidal meningocele presenting as airway obstruction and panhypopituitarism: Radiological findings and the role of CSF flow analysis.Radiology case reports · 2026Article
- Review
- Postoperative management of diabetes insipidus in a pediatric patient with Rathke's cleft cyst undergoing transsphenoidal endonasal surgery.Surgical neurology international · 2025Article
- How to Implement Clinical 7T MRI-Practical Considerations and Experience with Ultra-High-Field MRI.Bioengineering (Basel, Switzerland) · 2024Article
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Authors and funding
6 authors.
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Abstract
background and purposeA cleftlike nonenhancing hypointensity was observed repeatedly in the pituitary gland at the adenohypophysis/neurohypophysis border on contrast-enhanced 3D fat-saturated T1-MPRAGE using clinical 7T MRI. Our primary goal was to assess the prevalence of this finding. The secondary goals were to evaluate the frequency of other incidental pituitary lesions, MRI artifacts, and their effect on pituitary imaging on the contrast-enhanced 3D fat-saturated T1 MPRAGE at 7T. MATERIALS AND
methodsOne hundred patients who underwent 7T neuroimaging between October 27, 2021, and August 10, 2023, were included. Each case was evaluated for cleftlike pituitary hypointensity, pituitary masses, and artifacts on contrast-enhanced 3D fat-saturated T1 MPRAGE. Follow-up examinations were evaluated if present. The average prevalence for each finding was calculated, as were descriptive statistics for age and sex.
resultsA cleftlike hypointensity was present in 66% of 7T MRIs. There were no significant differences between the "cleftlike present" and "cleftlike absent" groups regarding sex (
conclusionsA cleftlike nonenhancing hypointensity was frequently seen on the contrast-enhanced 3D fat-saturated T1 MPRAGE images at 7T MRI, which most likely represents a normal embryologic Rathke cleft remnant and cannot be seen in lower-field-strength MRIs. Susceptibility and motion artifacts are common in the sella. They may affect image quality, and the artifacts at 7T may lead to an underestimation of the prevalence of the Rathke cleft and other incidental findings.
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