Evidence map›Paper›PMID 38913872›Full record

ArticleRNA biology2024

The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis.

Christian D Mutti, Lindsey Van Haute, Michal Minczuk

Abstract read
In one paragraph

Article in RNA biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christian D MuttiMRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.
Lindsey Van HauteMRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.
Michal MinczukMRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.ORCID 0000-0001-8242-1420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ribosomes are large macromolecular complexes composed of both proteins and RNA, that require a plethora of factors and post-transcriptional modifications for their biogenesis. In human mitochondria, the ribosomal RNA is post-transcriptionally modified at ten sites. The N4-methylcytidine (m

Indexed as

MethyltransferasesMitochondrial RibosomesRNA, RibosomalHumansMethylationMitochondriaMethyltransferasesMETTL15 protein, humanMRM2 protein, humanRNA, RibosomalRNA, ribosomal, 12SchaperoneepitranscriptomicsmethyltransferasemitochondriaMitochondrial ribosomeribosomal RNA

Identifiers

PMID38913872
PMCPMC11197891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.